L908-0343 Screening compound: 3-{2-[4-(4-fluorophenyl)piperazino]-2-oxoethyl}-9-methyl-8,9,10,11-tetrahydro[1]benzothieno[3,2-e][1,2,4]triazolo[1,5-c]pyrimidin-2(3H)-one

L908-0343 Screening compound: 3-{2-[4-(4-fluorophenyl)piperazino]-2-oxoethyl}-9-methyl-8,9,10,11-tetrahydro[1]benzothieno[3,2-e][1,2,4]triazolo[1,5-c]pyrimidin-2(3H)-one
L908-0343 Screening compound: 3-{2-[4-(4-fluorophenyl)piperazino]-2-oxoethyl}-9-methyl-8,9,10,11-tetrahydro[1]benzothieno[3,2-e][1,2,4]triazolo[1,5-c]pyrimidin-2(3H)-one alternative view

Chemical Structure Depiction of ChemDiv screening compound L908-0343
3-{2-[4-(4-fluorophenyl)piperazino]-2-oxoethyl}-9-methyl-8,9,10,11-tetrahydro[1]benzothieno[3,2-e][1,2,4]triazolo[1,5-c]pyrimidin-2(3H)-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L908-0343

Molecular Formula

C24H25FN6O2S (C24 H25 FN6 O2 S)

Compound Name

3-{2-[4-(4-fluorophenyl)piperazino]-2-oxoethyl}-9-methyl-8,9,10,11-tetrahydro[1]benzothieno[3,2-e][1,2,4]triazolo[1,5-c]pyrimidin-2(3H)-one

IUPAC name

5-{2-[4-(4-fluorophenyl)piperazin-1-yl]-2-oxoethyl}-13-methyl-10-thia-3568-tetraazatetracyclo[7.7.0.0^{26}.0^{1116}]hexadeca-1(9)2711(16)-tetraen-4-one

SMILES

CC(CC1)Cc2c1c(C(N(C=N1)N3CC(N(CC4)CCN4c(cc4)ccc4F)=O)=NC3=O)c1s2

InChI

InChI=1S/C24H25FN6O2S/c1-15-2-7-18-19(12-15)34-23-21(18)22-27-24(33)30(31(22)14-26-23)13-20(32)29-10-8-28(9-11-29)17-5-3-16(25)4-6-17/h3-6,14-15H,2,7-13H2,1H3/t15-/m1/s1

InChI Key

MSIXABITAVEPMD-OAHLLOKOSA-N

MDL Number (MFCD)

MFCD27485833

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

480.57

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

3.328

Distribution Coefficient, logD

-2.271

Water Solubility, LogSw

-3.73

Polar Surface Area

57.444

Acid Dissociation Constant (pKa)

20.36

Base Dissociation Constant (pKb)

13.00

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

41.70

L908-0343 in Drug Discovery

Included in Screening Libraries

Allosteric Kinases Inhibitors Library (23117 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Female
  • Congenital
  • Skin
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with L908-0343 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L908-0343?
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What is the minimum amount of L908-0343 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L908-0343
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L908-0343
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L908-0343 available by request