L908-0348 Screening compound: N~1~-[4-(diethylamino)-2-methylphenyl]-2-[9-methyl-2-oxo-8,9,10,11-tetrahydro[1]benzothieno[3,2-e][1,2,4]triazolo[1,5-c]pyrimidin-3(2H)-yl]acetamide

L908-0348 Screening compound: N~1~-[4-(diethylamino)-2-methylphenyl]-2-[9-methyl-2-oxo-8,9,10,11-tetrahydro[1]benzothieno[3,2-e][1,2,4]triazolo[1,5-c]pyrimidin-3(2H)-yl]acetamide
L908-0348 Screening compound: N~1~-[4-(diethylamino)-2-methylphenyl]-2-[9-methyl-2-oxo-8,9,10,11-tetrahydro[1]benzothieno[3,2-e][1,2,4]triazolo[1,5-c]pyrimidin-3(2H)-yl]acetamide alternative view

Chemical Structure Depiction of ChemDiv screening compound L908-0348
N~1~-[4-(diethylamino)-2-methylphenyl]-2-[9-methyl-2-oxo-8,9,10,11-tetrahydro[1]benzothieno[3,2-e][1,2,4]triazolo[1,5-c]pyrimidin-3(2H)-yl]acetamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L908-0348

Molecular Formula

C25H30N6O2S (C25 H30 N6 O2 S)

Compound Name

N~1~-[4-(diethylamino)-2-methylphenyl]-2-[9-methyl-2-oxo-8,9,10,11-tetrahydro[1]benzothieno[3,2-e][1,2,4]triazolo[1,5-c]pyrimidin-3(2H)-yl]acetamide

IUPAC name

N-[4-(diethylamino)-2-methylphenyl]-2-{13-methyl-4-oxo-10-thia-3568-tetraazatetracyclo[7.7.0.0^{26}.0^{1116}]hexadeca-1(9)2711(16)-tetraen-5-yl}acetamide

SMILES

CCN(CC)c(cc1)cc(C)c1NC(CN1N(C=Nc2c3c(CCC(C)C4)c4s2)C3=NC1=O)=O

InChI

InChI=1S/C25H30N6O2S/c1-5-29(6-2)17-8-10-19(16(4)12-17)27-21(32)13-30-25(33)28-23-22-18-9-7-15(3)11-20(18)34-24(22)26-14-31(23)30/h8,10,12,14-15H,5-7,9,11,13H2,1-4H3,(H,27,32)/t15-/m1/s1

InChI Key

ASGCBUYZVZSBLX-OAHLLOKOSA-N

MDL Number (MFCD)

MFCD27485834

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

478.62

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

4.369

Distribution Coefficient, logD

0.750

Water Solubility, LogSw

-4.48

Polar Surface Area

62.979

Acid Dissociation Constant (pKa)

12.76

Base Dissociation Constant (pKb)

11.02

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

44.00

L908-0348 in Drug Discovery

Included in Screening Libraries

Allosteric Kinases Inhibitors Library (23117 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Female
  • Congenital
  • Skin
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with L908-0348 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L908-0348?
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What is the minimum amount of L908-0348 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L908-0348
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L908-0348
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L908-0348 available by request