L910-0299 Screening compound: N-[3-(5-{1-[2-(2-methylphenyl)acetyl]piperidin-4-yl}-1,2,4-oxadiazol-3-yl)phenyl]propanamide

L910-0299 Screening compound: N-[3-(5-{1-[2-(2-methylphenyl)acetyl]piperidin-4-yl}-1,2,4-oxadiazol-3-yl)phenyl]propanamide
L910-0299 Screening compound: N-[3-(5-{1-[2-(2-methylphenyl)acetyl]piperidin-4-yl}-1,2,4-oxadiazol-3-yl)phenyl]propanamide alternative view

Chemical Structure Depiction of ChemDiv screening compound L910-0299
N-[3-(5-{1-[2-(2-methylphenyl)acetyl]piperidin-4-yl}-1,2,4-oxadiazol-3-yl)phenyl]propanamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L910-0299

Molecular Formula

C25H28N4O3 (C25 H28 N4 O3)

Compound Name

N-[3-(5-{1-[2-(2-methylphenyl)acetyl]piperidin-4-yl}-1,2,4-oxadiazol-3-yl)phenyl]propanamide

IUPAC name

N-[3-(5-{1-[2-(2-methylphenyl)acetyl]piperidin-4-yl}-124-oxadiazol-3-yl)phenyl]propanamide

SMILES

CCC(Nc1cccc(-c2noc(C(CC3)CCN3C(Cc3c(C)cccc3)=O)n2)c1)=O

InChI

InChI=1S/C25H28N4O3/c1-3-22(30)26-21-10-6-9-20(15-21)24-27-25(32-28-24)18-11-13-29(14-12-18)23(31)16-19-8-5-4-7-17(19)2/h4-10,15,18H,3,11-14,16H2,1-2H3,(H,26,30)

InChI Key

ITJREVIHUZACAU-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27486006

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

432.52

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

5.167

Distribution Coefficient, logD

5.167

Water Solubility, LogSw

-4.98

Polar Surface Area

70.914

Acid Dissociation Constant (pKa)

12.96

Base Dissociation Constant (pKb)

1.68

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

36.00

L910-0299 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

PPI Inhibitors Tripeptide Mimetics (23972 compounds)

Protein-Protein Interaction Library (218420 compounds)

Beyond the Flatland Library sp3 enriched (92988 compounds)

Histone Deacetylases (HDAC) Targeted Library (9760 compounds)

Peptidomimetic Library (37031 compounds)

Included in 1.7M Stock Database

Mechanism of action:
  • PPI modulators
  • PPI modulators
  • Epigenetic
  • PPI modulators
Structure:
  • Mimetics
  • Cyclic compounds
  • Mimetics
Therapeutical areas:
  • Cancer
  • Nervous system
  • Hemic and lymphatic
  • Endocrine
  • Immune system

References: we are preparing a list of scientific research reports with L910-0299 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L910-0299?
Check Price and Availability of L910-0299, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L910-0299 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L910-0299
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L910-0299
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L910-0299 available by request