L911-0123 Screening compound: N-(4-{5-[1-(1H-indole-4-carbonyl)piperidin-4-yl]-1,2,4-oxadiazol-3-yl}phenyl)acetamide

L911-0123 Screening compound: N-(4-{5-[1-(1H-indole-4-carbonyl)piperidin-4-yl]-1,2,4-oxadiazol-3-yl}phenyl)acetamide
L911-0123 Screening compound: N-(4-{5-[1-(1H-indole-4-carbonyl)piperidin-4-yl]-1,2,4-oxadiazol-3-yl}phenyl)acetamide alternative view

Chemical Structure Depiction of ChemDiv screening compound L911-0123
N-(4-{5-[1-(1H-indole-4-carbonyl)piperidin-4-yl]-1,2,4-oxadiazol-3-yl}phenyl)acetamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L911-0123

Molecular Formula

C24H23N5O3 (C24 H23 N5 O3)

Compound Name

N-(4-{5-[1-(1H-indole-4-carbonyl)piperidin-4-yl]-1,2,4-oxadiazol-3-yl}phenyl)acetamide

IUPAC name

N-(4-{5-[1-(1H-indole-4-carbonyl)piperidin-4-yl]-124-oxadiazol-3-yl}phenyl)acetamide

SMILES

CC(Nc(cc1)ccc1-c1noc(C(CC2)CCN2C(c2c(cc[nH]3)c3ccc2)=O)n1)=O

InChI

InChI=1S/C24H23N5O3/c1-15(30)26-18-7-5-16(6-8-18)22-27-23(32-28-22)17-10-13-29(14-11-17)24(31)20-3-2-4-21-19(20)9-12-25-21/h2-9,12,17,25H,10-11,13-14H2,1H3,(H,26,30)

InChI Key

LPRYITTYHZSTDA-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27486082

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

429.48

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

3.459

Distribution Coefficient, logD

3.459

Water Solubility, LogSw

-3.68

Polar Surface Area

81.336

Acid Dissociation Constant (pKa)

13.34

Base Dissociation Constant (pKb)

-0.11

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

25.00

L911-0123 in Drug Discovery

Included in Screening Libraries

3D-Diversity Natural-Product-Like Library (18102 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

GPCR Targeted Library (31838 compounds)

Indole Derivatives (10091 compounds)

PPI Inhibitors Tripeptide Mimetics (23972 compounds)

Protein-Protein Interaction Library (218420 compounds)

Beyond the Flatland Library sp3 enriched (92988 compounds)

Peptidomimetic Library (37031 compounds)

Included in 1.7M Stock Database

Structure:
  • 3D
  • Cyclic compounds
  • Mimetics
  • Cyclic compounds
  • Mimetics
Therapeutical areas:
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
Targets:
  • GPCR
Mechanism of action:
  • Receptor's ligands
  • PPI modulators
  • PPI modulators
  • PPI modulators

References: we are preparing a list of scientific research reports with L911-0123 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L911-0123?
Check Price and Availability of L911-0123, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L911-0123 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L911-0123
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L911-0123
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L911-0123 available by request