L914-0147 Screening compound: 3-[(5-{1,4-dioxa-8-azaspiro[4.5]decane-8-carbonyl}-1,2,4-oxadiazol-3-yl)methyl]-2,3-dihydro-1,3-benzoxazol-2-one

L914-0147 Screening compound: 3-[(5-{1,4-dioxa-8-azaspiro[4.5]decane-8-carbonyl}-1,2,4-oxadiazol-3-yl)methyl]-2,3-dihydro-1,3-benzoxazol-2-one
L914-0147 Screening compound: 3-[(5-{1,4-dioxa-8-azaspiro[4.5]decane-8-carbonyl}-1,2,4-oxadiazol-3-yl)methyl]-2,3-dihydro-1,3-benzoxazol-2-one alternative view

Chemical Structure Depiction of ChemDiv screening compound L914-0147
3-[(5-{1,4-dioxa-8-azaspiro[4.5]decane-8-carbonyl}-1,2,4-oxadiazol-3-yl)methyl]-2,3-dihydro-1,3-benzoxazol-2-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L914-0147

Molecular Formula

C18H18N4O6 (C18 H18 N4 O6)

Compound Name

3-[(5-{1,4-dioxa-8-azaspiro[4.5]decane-8-carbonyl}-1,2,4-oxadiazol-3-yl)methyl]-2,3-dihydro-1,3-benzoxazol-2-one

IUPAC name

3-[(5-{14-dioxa-8-azaspiro[4.5]decane-8-carbonyl}-124-oxadiazol-3-yl)methyl]-23-dihydro-13-benzoxazol-2-one

SMILES

O=C(c1nc(CN(c(cccc2)c2O2)C2=O)no1)N(CC1)CCC11OCCO1

InChI

InChI=1S/C18H18N4O6/c23-16(21-7-5-18(6-8-21)25-9-10-26-18)15-19-14(20-28-15)11-22-12-3-1-2-4-13(12)27-17(22)24/h1-4H,5-11H2

InChI Key

MEYRZDSUFUGIQU-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27486256

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

386.36

Hydrogen Bond Acceptors Count

10.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

10

Partition Coefficient, logP

0.804

Distribution Coefficient, logD

0.804

Water Solubility, LogSw

-1.50

Polar Surface Area

87.092

Acid Dissociation Constant (pKa)

27.45

Base Dissociation Constant (pKb)

-1.43

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

44.40

L914-0147 in Drug Discovery

Included in Screening Libraries

PPI Inhibitors Tripeptide Mimetics (23972 compounds)

Peptidomimetic Library (37031 compounds)

Included in 1.7M Stock Database

Mechanism of action:
  • PPI modulators
  • PPI modulators
Structure:
  • Mimetics
  • Mimetics

References: we are preparing a list of scientific research reports with L914-0147 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L914-0147?
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What is the minimum amount of L914-0147 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L914-0147
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L914-0147
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L914-0147 available by request