L914-0286 Screening compound: N-{[4-(dimethylamino)phenyl]methyl}-3-[(2-oxo-2,3-dihydro-1,3-benzoxazol-3-yl)methyl]-1,2,4-oxadiazole-5-carboxamide

L914-0286 Screening compound: N-{[4-(dimethylamino)phenyl]methyl}-3-[(2-oxo-2,3-dihydro-1,3-benzoxazol-3-yl)methyl]-1,2,4-oxadiazole-5-carboxamide
L914-0286 Screening compound: N-{[4-(dimethylamino)phenyl]methyl}-3-[(2-oxo-2,3-dihydro-1,3-benzoxazol-3-yl)methyl]-1,2,4-oxadiazole-5-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound L914-0286
N-{[4-(dimethylamino)phenyl]methyl}-3-[(2-oxo-2,3-dihydro-1,3-benzoxazol-3-yl)methyl]-1,2,4-oxadiazole-5-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L914-0286

Molecular Formula

C20H19N5O4 (C20 H19 N5 O4)

Compound Name

N-{[4-(dimethylamino)phenyl]methyl}-3-[(2-oxo-2,3-dihydro-1,3-benzoxazol-3-yl)methyl]-1,2,4-oxadiazole-5-carboxamide

IUPAC name

N-{[4-(dimethylamino)phenyl]methyl}-3-[(2-oxo-23-dihydro-13-benzoxazol-3-yl)methyl]-124-oxadiazole-5-carboxamide

SMILES

CN(C)c1ccc(CNC(c2nc(CN(c(cccc3)c3O3)C3=O)no2)=O)cc1

InChI

InChI=1S/C20H19N5O4/c1-24(2)14-9-7-13(8-10-14)11-21-18(26)19-22-17(23-29-19)12-25-15-5-3-4-6-16(15)28-20(25)27/h3-10H,11-12H2,1-2H3,(H,21,26)

InChI Key

WEKCRZPQBVEDFE-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27486284

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

393.4

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

9

Partition Coefficient, logP

2.245

Distribution Coefficient, logD

2.229

Water Solubility, LogSw

-2.79

Polar Surface Area

83.224

Acid Dissociation Constant (pKa)

12.31

Base Dissociation Constant (pKb)

5.96

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

20.00

L914-0286 in Drug Discovery

Included in Screening Libraries

PPI Inhibitors Tripeptide Mimetics (23972 compounds)

Peptidomimetic Library (37031 compounds)

Included in 1.7M Stock Database

Mechanism of action:
  • PPI modulators
  • PPI modulators
Structure:
  • Mimetics
  • Mimetics

References: we are preparing a list of scientific research reports with L914-0286 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L914-0286?
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What is the minimum amount of L914-0286 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L914-0286
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L914-0286
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L914-0286 available by request