L914-0341 Screening compound: N-({1-[(2-fluorophenyl)methyl]piperidin-4-yl}methyl)-3-[(2-oxo-2,3-dihydro-1,3-benzoxazol-3-yl)methyl]-1,2,4-oxadiazole-5-carboxamide

L914-0341 Screening compound: N-({1-[(2-fluorophenyl)methyl]piperidin-4-yl}methyl)-3-[(2-oxo-2,3-dihydro-1,3-benzoxazol-3-yl)methyl]-1,2,4-oxadiazole-5-carboxamide
L914-0341 Screening compound: N-({1-[(2-fluorophenyl)methyl]piperidin-4-yl}methyl)-3-[(2-oxo-2,3-dihydro-1,3-benzoxazol-3-yl)methyl]-1,2,4-oxadiazole-5-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound L914-0341
N-({1-[(2-fluorophenyl)methyl]piperidin-4-yl}methyl)-3-[(2-oxo-2,3-dihydro-1,3-benzoxazol-3-yl)methyl]-1,2,4-oxadiazole-5-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L914-0341

Molecular Formula

C24H24FN5O4 (C24 H24 FN5 O4)

Compound Name

N-({1-[(2-fluorophenyl)methyl]piperidin-4-yl}methyl)-3-[(2-oxo-2,3-dihydro-1,3-benzoxazol-3-yl)methyl]-1,2,4-oxadiazole-5-carboxamide

IUPAC name

N-({1-[(2-fluorophenyl)methyl]piperidin-4-yl}methyl)-3-[(2-oxo-23-dihydro-13-benzoxazol-3-yl)methyl]-124-oxadiazole-5-carboxamide

SMILES

O=C(c1nc(CN(c(cccc2)c2O2)C2=O)no1)NCC1CCN(Cc(cccc2)c2F)CC1

InChI

InChI=1S/C24H24FN5O4/c25-18-6-2-1-5-17(18)14-29-11-9-16(10-12-29)13-26-22(31)23-27-21(28-34-23)15-30-19-7-3-4-8-20(19)33-24(30)32/h1-8,16H,9-15H2,(H,26,31)

InChI Key

OAHARONBBMRIBK-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27486291

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

465.48

Hydrogen Bond Acceptors Count

9.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

9

Partition Coefficient, logP

3.072

Distribution Coefficient, logD

1.282

Water Solubility, LogSw

-3.56

Polar Surface Area

84.152

Acid Dissociation Constant (pKa)

13.03

Base Dissociation Constant (pKb)

9.18

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

33.30

L914-0341 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

PPI Inhibitors Tripeptide Mimetics (23972 compounds)

Peptidomimetic Library (37031 compounds)

Included in 1.7M Stock Database

Mechanism of action:
  • PPI modulators
  • PPI modulators
Structure:
  • Mimetics
  • Mimetics

References: we are preparing a list of scientific research reports with L914-0341 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L914-0341?
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What is the minimum amount of L914-0341 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L914-0341
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L914-0341
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L914-0341 available by request