L918-1003 Screening compound: N-{3-[3-(1-methanesulfonylpiperidin-4-yl)-1,2,4-oxadiazol-5-yl]phenyl}benzamide

L918-1003 Screening compound: N-{3-[3-(1-methanesulfonylpiperidin-4-yl)-1,2,4-oxadiazol-5-yl]phenyl}benzamide
L918-1003 Screening compound: N-{3-[3-(1-methanesulfonylpiperidin-4-yl)-1,2,4-oxadiazol-5-yl]phenyl}benzamide alternative view

Chemical Structure Depiction of ChemDiv screening compound L918-1003
N-{3-[3-(1-methanesulfonylpiperidin-4-yl)-1,2,4-oxadiazol-5-yl]phenyl}benzamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L918-1003

Molecular Formula

C21H22N4O4S (C21 H22 N4 O4 S)

Compound Name

N-{3-[3-(1-methanesulfonylpiperidin-4-yl)-1,2,4-oxadiazol-5-yl]phenyl}benzamide

IUPAC name

N-{3-[3-(1-methanesulfonylpiperidin-4-yl)-124-oxadiazol-5-yl]phenyl}benzamide

SMILES

CS(N(CC1)CCC1c1noc(-c2cc(NC(c3ccccc3)=O)ccc2)n1)(=O)=O

InChI

InChI=1S/C21H22N4O4S/c1-30(27,28)25-12-10-15(11-13-25)19-23-21(29-24-19)17-8-5-9-18(14-17)22-20(26)16-6-3-2-4-7-16/h2-9,14-15H,10-13H2,1H3,(H,22,26)

InChI Key

KLQCOZSLRYEPTO-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27486410

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

426.5

Hydrogen Bond Acceptors Count

10.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

3.245

Distribution Coefficient, logD

3.245

Water Solubility, LogSw

-3.53

Polar Surface Area

86.210

Acid Dissociation Constant (pKa)

11.78

Base Dissociation Constant (pKb)

-1.75

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

28.60

L918-1003 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

GPCR Targeted Library (31838 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
Targets:
  • GPCR
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with L918-1003 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L918-1003?
Check Price and Availability of L918-1003, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L918-1003 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L918-1003
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L918-1003
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L918-1003 available by request