L918-1846 Screening compound: 4-[5-(4-chlorophenyl)-1,2,4-oxadiazol-3-yl]-1-(5,6,7,8-tetrahydronaphthalene-2-sulfonyl)piperidine

L918-1846 Screening compound: 4-[5-(4-chlorophenyl)-1,2,4-oxadiazol-3-yl]-1-(5,6,7,8-tetrahydronaphthalene-2-sulfonyl)piperidine
L918-1846 Screening compound: 4-[5-(4-chlorophenyl)-1,2,4-oxadiazol-3-yl]-1-(5,6,7,8-tetrahydronaphthalene-2-sulfonyl)piperidine alternative view

Chemical Structure Depiction of ChemDiv screening compound L918-1846
4-[5-(4-chlorophenyl)-1,2,4-oxadiazol-3-yl]-1-(5,6,7,8-tetrahydronaphthalene-2-sulfonyl)piperidine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L918-1846

Molecular Formula

C23H24ClN3O3S (C23 H24 ClN3 O3 S)

Compound Name

4-[5-(4-chlorophenyl)-1,2,4-oxadiazol-3-yl]-1-(5,6,7,8-tetrahydronaphthalene-2-sulfonyl)piperidine

IUPAC name

4-[5-(4-chlorophenyl)-124-oxadiazol-3-yl]-1-(5678-tetrahydronaphthalene-2-sulfonyl)piperidine

SMILES

O=S(c1cc(CCCC2)c2cc1)(N(CC1)CCC1c1noc(-c(cc2)ccc2Cl)n1)=O

InChI

InChI=1S/C23H24ClN3O3S/c24-20-8-5-18(6-9-20)23-25-22(26-30-23)17-11-13-27(14-12-17)31(28,29)21-10-7-16-3-1-2-4-19(16)15-21/h5-10,15,17H,1-4,11-14H2

InChI Key

ILWSWQNGICLDSZ-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27486508

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

457.98

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

5.920

Distribution Coefficient, logD

5.920

Water Solubility, LogSw

-6.38

Polar Surface Area

63.276

Acid Dissociation Constant (pKa)

25.48

Base Dissociation Constant (pKb)

-2.96

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

39.10

L918-1846 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Adenosine Receptors Targeted Library (19896 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Nervous system
  • Eye
  • Cardiovascular
Targets:
  • GPCR
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with L918-1846 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L918-1846?
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What is the minimum amount of L918-1846 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L918-1846
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L918-1846
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L918-1846 available by request