L918-2206 Screening compound: 4-[5-(3-fluorophenyl)-1,2,4-oxadiazol-3-yl]-1-methanesulfonylpiperidine

L918-2206 Screening compound: 4-[5-(3-fluorophenyl)-1,2,4-oxadiazol-3-yl]-1-methanesulfonylpiperidine
L918-2206 Screening compound: 4-[5-(3-fluorophenyl)-1,2,4-oxadiazol-3-yl]-1-methanesulfonylpiperidine alternative view

Chemical Structure Depiction of ChemDiv screening compound L918-2206
4-[5-(3-fluorophenyl)-1,2,4-oxadiazol-3-yl]-1-methanesulfonylpiperidine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L918-2206

Molecular Formula

C14H16FN3O3S (C14 H16 FN3 O3 S)

Compound Name

4-[5-(3-fluorophenyl)-1,2,4-oxadiazol-3-yl]-1-methanesulfonylpiperidine

IUPAC name

4-[5-(3-fluorophenyl)-124-oxadiazol-3-yl]-1-methanesulfonylpiperidine

SMILES

CS(N(CC1)CCC1c1noc(-c2cc(F)ccc2)n1)(=O)=O

InChI

InChI=1S/C14H16FN3O3S/c1-22(19,20)18-7-5-10(6-8-18)13-16-14(21-17-13)11-3-2-4-12(15)9-11/h2-4,9-10H,5-8H2,1H3

InChI Key

HLLKQJHZNXTZTN-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27486619

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

325.36

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

3.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

2.341

Distribution Coefficient, logD

2.341

Water Solubility, LogSw

-2.73

Polar Surface Area

63.119

Acid Dissociation Constant (pKa)

24.48

Base Dissociation Constant (pKb)

-3.31

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

42.90

L918-2206 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Protein-Protein Interaction Library (218420 compounds)

Targeted Diversity Library (40567 compounds)

Beyond the Flatland Library sp3 enriched (92988 compounds)

Included in 1.7M Stock Database

Mechanism of action:
  • PPI modulators
Structure:
  • Cyclic compounds

References: we are preparing a list of scientific research reports with L918-2206 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L918-2206?
Check Price and Availability of L918-2206, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L918-2206 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L918-2206
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L918-2206
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L918-2206 available by request