L918-2216 Screening compound: 1-[(5-bromothiophen-2-yl)sulfonyl]-4-[5-(3-fluorophenyl)-1,2,4-oxadiazol-3-yl]piperidine

L918-2216 Screening compound: 1-[(5-bromothiophen-2-yl)sulfonyl]-4-[5-(3-fluorophenyl)-1,2,4-oxadiazol-3-yl]piperidine
L918-2216 Screening compound: 1-[(5-bromothiophen-2-yl)sulfonyl]-4-[5-(3-fluorophenyl)-1,2,4-oxadiazol-3-yl]piperidine alternative view

Chemical Structure Depiction of ChemDiv screening compound L918-2216
1-[(5-bromothiophen-2-yl)sulfonyl]-4-[5-(3-fluorophenyl)-1,2,4-oxadiazol-3-yl]piperidine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L918-2216

Molecular Formula

C17H15BrFN3O3S2 (C17 H15 BrFN3 O3 S2)

Compound Name

1-[(5-bromothiophen-2-yl)sulfonyl]-4-[5-(3-fluorophenyl)-1,2,4-oxadiazol-3-yl]piperidine

IUPAC name

1-[(5-bromothiophen-2-yl)sulfonyl]-4-[5-(3-fluorophenyl)-124-oxadiazol-3-yl]piperidine

SMILES

O=S(c(s1)ccc1Br)(N(CC1)CCC1c1noc(-c2cc(F)ccc2)n1)=O

InChI

InChI=1S/C17H15BrFN3O3S2/c18-14-4-5-15(26-14)27(23,24)22-8-6-11(7-9-22)16-20-17(25-21-16)12-2-1-3-13(19)10-12/h1-5,10-11H,6-9H2

InChI Key

BCIMFONKMIMPPN-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27486625

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

472.36

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

4.555

Distribution Coefficient, logD

4.555

Water Solubility, LogSw

-4.42

Polar Surface Area

64.374

Acid Dissociation Constant (pKa)

26.56

Base Dissociation Constant (pKb)

-3.31

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

29.40

L918-2216 in Drug Discovery

Included in Screening Libraries

Adenosine Receptors Targeted Library (19896 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Nervous system
  • Eye
  • Cardiovascular
Targets:
  • GPCR
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with L918-2216 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L918-2216?
Check Price and Availability of L918-2216, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L918-2216 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L918-2216
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L918-2216
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L918-2216 available by request