L918-2221 Screening compound: 1-(5-chloro-2-methoxybenzenesulfonyl)-4-[5-(3-fluorophenyl)-1,2,4-oxadiazol-3-yl]piperidine

L918-2221 Screening compound: 1-(5-chloro-2-methoxybenzenesulfonyl)-4-[5-(3-fluorophenyl)-1,2,4-oxadiazol-3-yl]piperidine
L918-2221 Screening compound: 1-(5-chloro-2-methoxybenzenesulfonyl)-4-[5-(3-fluorophenyl)-1,2,4-oxadiazol-3-yl]piperidine alternative view

Chemical Structure Depiction of ChemDiv screening compound L918-2221
1-(5-chloro-2-methoxybenzenesulfonyl)-4-[5-(3-fluorophenyl)-1,2,4-oxadiazol-3-yl]piperidine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L918-2221

Molecular Formula

C20H19ClFN3O4S (C20 H19 ClFN3 O4 S)

Compound Name

1-(5-chloro-2-methoxybenzenesulfonyl)-4-[5-(3-fluorophenyl)-1,2,4-oxadiazol-3-yl]piperidine

IUPAC name

1-(5-chloro-2-methoxybenzenesulfonyl)-4-[5-(3-fluorophenyl)-124-oxadiazol-3-yl]piperidine

SMILES

COc(ccc(Cl)c1)c1S(N(CC1)CCC1c1noc(-c2cc(F)ccc2)n1)(=O)=O

InChI

InChI=1S/C20H19ClFN3O4S/c1-28-17-6-5-15(21)12-18(17)30(26,27)25-9-7-13(8-10-25)19-23-20(29-24-19)14-3-2-4-16(22)11-14/h2-6,11-13H,7-10H2,1H3

InChI Key

QRTBZHMBCPQTLI-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27486630

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

451.91

Hydrogen Bond Acceptors Count

9.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

4.306

Distribution Coefficient, logD

4.306

Water Solubility, LogSw

-4.59

Polar Surface Area

70.986

Acid Dissociation Constant (pKa)

26.56

Base Dissociation Constant (pKb)

-3.31

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

30.00

L918-2221 in Drug Discovery

Included in Screening Libraries

Adenosine Receptors Targeted Library (19896 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Nervous system
  • Eye
  • Cardiovascular
Targets:
  • GPCR
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with L918-2221 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L918-2221?
Check Price and Availability of L918-2221, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L918-2221 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L918-2221
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L918-2221
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L918-2221 available by request