L918-2277 Screening compound: 4-[5-(3-methoxyphenyl)-1,2,4-oxadiazol-3-yl]-1-(thiophene-2-sulfonyl)piperidine

L918-2277 Screening compound: 4-[5-(3-methoxyphenyl)-1,2,4-oxadiazol-3-yl]-1-(thiophene-2-sulfonyl)piperidine
L918-2277 Screening compound: 4-[5-(3-methoxyphenyl)-1,2,4-oxadiazol-3-yl]-1-(thiophene-2-sulfonyl)piperidine alternative view

Chemical Structure Depiction of ChemDiv screening compound L918-2277
4-[5-(3-methoxyphenyl)-1,2,4-oxadiazol-3-yl]-1-(thiophene-2-sulfonyl)piperidine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L918-2277

Molecular Formula

C18H19N3O4S2 (C18 H19 N3 O4 S2)

Compound Name

4-[5-(3-methoxyphenyl)-1,2,4-oxadiazol-3-yl]-1-(thiophene-2-sulfonyl)piperidine

IUPAC name

4-[5-(3-methoxyphenyl)-124-oxadiazol-3-yl]-1-(thiophene-2-sulfonyl)piperidine

SMILES

COc1cccc(-c2nc(C(CC3)CCN3S(c3cccs3)(=O)=O)no2)c1

MDL Number (MFCD)

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

405.5

Hydrogen Bond Acceptors Count

9.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

3.572

Distribution Coefficient, logD

3.572

Water Solubility, LogSw

-3.68

Polar Surface Area

71.917

Acid Dissociation Constant (pKa)

26.56

Base Dissociation Constant (pKb)

-1.61

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

33.30

L918-2277 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Protein-Protein Interaction Library (218420 compounds)

Adenosine Receptors Targeted Library (19896 compounds)

Beyond the Flatland Library sp3 enriched (92988 compounds)

Included in 1.7M Stock Database

Mechanism of action:
  • PPI modulators
  • Receptor's ligands
Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Nervous system
  • Eye
  • Cardiovascular
Targets:
  • GPCR
Structure:
  • Cyclic compounds

References: we are preparing a list of scientific research reports with L918-2277 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L918-2277?
Check Price and Availability of L918-2277, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L918-2277 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L918-2277
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L918-2277
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L918-2277 available by request