L918-2340 Screening compound: 1-[(5-bromothiophen-2-yl)sulfonyl]-4-[5-(2-methylphenyl)-1,2,4-oxadiazol-3-yl]piperidine

L918-2340 Screening compound: 1-[(5-bromothiophen-2-yl)sulfonyl]-4-[5-(2-methylphenyl)-1,2,4-oxadiazol-3-yl]piperidine
L918-2340 Screening compound: 1-[(5-bromothiophen-2-yl)sulfonyl]-4-[5-(2-methylphenyl)-1,2,4-oxadiazol-3-yl]piperidine alternative view

Chemical Structure Depiction of ChemDiv screening compound L918-2340
1-[(5-bromothiophen-2-yl)sulfonyl]-4-[5-(2-methylphenyl)-1,2,4-oxadiazol-3-yl]piperidine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L918-2340

Molecular Formula

C18H18BrN3O3S2 (C18 H18 BrN3 O3 S2)

Compound Name

1-[(5-bromothiophen-2-yl)sulfonyl]-4-[5-(2-methylphenyl)-1,2,4-oxadiazol-3-yl]piperidine

IUPAC name

1-[(5-bromothiophen-2-yl)sulfonyl]-4-[5-(2-methylphenyl)-124-oxadiazol-3-yl]piperidine

SMILES

Cc(cccc1)c1-c1nc(C(CC2)CCN2S(c(s2)ccc2Br)(=O)=O)no1

InChI

InChI=1S/C18H18BrN3O3S2/c1-12-4-2-3-5-14(12)18-20-17(21-25-18)13-8-10-22(11-9-13)27(23,24)16-7-6-15(19)26-16/h2-7,13H,8-11H2,1H3

InChI Key

PKROIWBNQHZGIB-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27486718

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

468.4

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

4.691

Distribution Coefficient, logD

4.691

Water Solubility, LogSw

-4.45

Polar Surface Area

64.374

Acid Dissociation Constant (pKa)

26.56

Base Dissociation Constant (pKb)

-3.96

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

33.30

L918-2340 in Drug Discovery

Included in Screening Libraries

Adenosine Receptors Targeted Library (19896 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Nervous system
  • Eye
  • Cardiovascular
Targets:
  • GPCR
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with L918-2340 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L918-2340?
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What is the minimum amount of L918-2340 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L918-2340
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L918-2340
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L918-2340 available by request