L921-0079 Screening compound: 1-cyclohexyl-4-{[2-methyl-5-(4-methyl-1,3-thiazol-2-yl)thiophen-3-yl]sulfonyl}piperazine

L921-0079 Screening compound: 1-cyclohexyl-4-{[2-methyl-5-(4-methyl-1,3-thiazol-2-yl)thiophen-3-yl]sulfonyl}piperazine
L921-0079 Screening compound: 1-cyclohexyl-4-{[2-methyl-5-(4-methyl-1,3-thiazol-2-yl)thiophen-3-yl]sulfonyl}piperazine alternative view

Chemical Structure Depiction of ChemDiv screening compound L921-0079
1-cyclohexyl-4-{[2-methyl-5-(4-methyl-1,3-thiazol-2-yl)thiophen-3-yl]sulfonyl}piperazine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L921-0079

Molecular Formula

C19H27N3O2S3 (C19 H27 N3 O2 S3)

Compound Name

1-cyclohexyl-4-{[2-methyl-5-(4-methyl-1,3-thiazol-2-yl)thiophen-3-yl]sulfonyl}piperazine

IUPAC name

1-cyclohexyl-4-{[2-methyl-5-(4-methyl-13-thiazol-2-yl)thiophen-3-yl]sulfonyl}piperazine

SMILES

Cc1csc(-c2cc(S(N(CC3)CCN3C3CCCCC3)(=O)=O)c(C)s2)n1

InChI

InChI=1S/C19H27N3O2S3/c1-14-13-25-19(20-14)17-12-18(15(2)26-17)27(23,24)22-10-8-21(9-11-22)16-6-4-3-5-7-16/h12-13,16H,3-11H2,1-2H3

InChI Key

QMMURBAUVKSOMM-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27486779

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

425.64

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

4.343

Distribution Coefficient, logD

4.264

Water Solubility, LogSw

-4.14

Polar Surface Area

45.602

Acid Dissociation Constant (pKa)

28.39

Base Dissociation Constant (pKb)

6.70

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

63.20

L921-0079 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

GPCR Targeted Library (31838 compounds)

Protein Arginine Methyltransferases Library (27925 compounds)

Protein Kinases Inhibitors Library (36801 compounds)

SmartTM Library (51161 compounds)

Targeted Diversity Library (40567 compounds)

Akt-Targeted Library (14764 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Metabolic
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Nervous system
  • Hemic and lymphatic
  • Cardiovascular
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
Targets:
  • GPCR
  • Others
  • Kinases
  • Kinases
Mechanism of action:
  • Receptor's ligands
  • Epigenetic

References: we are preparing a list of scientific research reports with L921-0079 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L921-0079?
Check Price and Availability of L921-0079, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L921-0079 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L921-0079
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L921-0079
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L921-0079 available by request