L921-0123 Screening compound: 4-benzyl-1-{[2-methyl-5-(4-methyl-1,3-thiazol-2-yl)thiophen-3-yl]sulfonyl}piperidine

L921-0123 Screening compound: 4-benzyl-1-{[2-methyl-5-(4-methyl-1,3-thiazol-2-yl)thiophen-3-yl]sulfonyl}piperidine
L921-0123 Screening compound: 4-benzyl-1-{[2-methyl-5-(4-methyl-1,3-thiazol-2-yl)thiophen-3-yl]sulfonyl}piperidine alternative view

Chemical Structure Depiction of ChemDiv screening compound L921-0123
4-benzyl-1-{[2-methyl-5-(4-methyl-1,3-thiazol-2-yl)thiophen-3-yl]sulfonyl}piperidine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L921-0123

Molecular Formula

C21H24N2O2S3 (C21 H24 N2 O2 S3)

Compound Name

4-benzyl-1-{[2-methyl-5-(4-methyl-1,3-thiazol-2-yl)thiophen-3-yl]sulfonyl}piperidine

IUPAC name

4-benzyl-1-{[2-methyl-5-(4-methyl-13-thiazol-2-yl)thiophen-3-yl]sulfonyl}piperidine

SMILES

Cc1csc(-c2cc(S(N3CCC(Cc4ccccc4)CC3)(=O)=O)c(C)s2)n1

InChI

InChI=1S/C21H24N2O2S3/c1-15-14-26-21(22-15)19-13-20(16(2)27-19)28(24,25)23-10-8-18(9-11-23)12-17-6-4-3-5-7-17/h3-7,13-14,18H,8-12H2,1-2H3

InChI Key

BKDLELRWYRHWKR-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27486797

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

432.63

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

4

Partition Coefficient, logP

5.714

Distribution Coefficient, logD

5.714

Water Solubility, LogSw

-5.63

Polar Surface Area

42.237

Acid Dissociation Constant (pKa)

25.46

Base Dissociation Constant (pKb)

2.33

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

38.10

L921-0123 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Protein Kinases Inhibitors Library (36801 compounds)

SmartTM Library (51161 compounds)

Targeted Diversity Library (40567 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Nervous system
  • Hemic and lymphatic
  • Cardiovascular
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with L921-0123 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L921-0123?
Check Price and Availability of L921-0123, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L921-0123 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L921-0123
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L921-0123
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L921-0123 available by request