L921-0404 Screening compound: 1-{[5-(4,5-dimethyl-1,3-thiazol-2-yl)-2-methylthiophen-3-yl]sulfonyl}-1,2,3,4-tetrahydroquinoline

L921-0404 Screening compound: 1-{[5-(4,5-dimethyl-1,3-thiazol-2-yl)-2-methylthiophen-3-yl]sulfonyl}-1,2,3,4-tetrahydroquinoline
L921-0404 Screening compound: 1-{[5-(4,5-dimethyl-1,3-thiazol-2-yl)-2-methylthiophen-3-yl]sulfonyl}-1,2,3,4-tetrahydroquinoline alternative view

Chemical Structure Depiction of ChemDiv screening compound L921-0404
1-{[5-(4,5-dimethyl-1,3-thiazol-2-yl)-2-methylthiophen-3-yl]sulfonyl}-1,2,3,4-tetrahydroquinoline

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L921-0404

Molecular Formula

C19H20N2O2S3 (C19 H20 N2 O2 S3)

Compound Name

1-{[5-(4,5-dimethyl-1,3-thiazol-2-yl)-2-methylthiophen-3-yl]sulfonyl}-1,2,3,4-tetrahydroquinoline

IUPAC name

1-{[5-(45-dimethyl-13-thiazol-2-yl)-2-methylthiophen-3-yl]sulfonyl}-1234-tetrahydroquinoline

SMILES

Cc1c(C)sc(-c2cc(S(N(CCC3)c4c3cccc4)(=O)=O)c(C)s2)n1

InChI

InChI=1S/C19H20N2O2S3/c1-12-13(2)25-19(20-12)17-11-18(14(3)24-17)26(22,23)21-10-6-8-15-7-4-5-9-16(15)21/h4-5,7,9,11H,6,8,10H2,1-3H3

InChI Key

WRORUCRWBIWQOJ-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27486863

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

404.58

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

3.00

Number of Nitrogen and Oxygen Atoms

4

Partition Coefficient, logP

4.830

Distribution Coefficient, logD

4.830

Water Solubility, LogSw

-4.58

Polar Surface Area

42.720

Acid Dissociation Constant (pKa)

24.92

Base Dissociation Constant (pKb)

3.48

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

31.60

L921-0404 in Drug Discovery

Included in Screening Libraries

Antiviral Library (67538 compounds)

Protein Arginine Methyltransferases Library (27925 compounds)

Protein Kinases Inhibitors Library (36801 compounds)

SmartTM Library (51161 compounds)

Targeted Diversity Library (40567 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Antiviral
  • Infections
  • Immune system
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Metabolic
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Nervous system
  • Hemic and lymphatic
  • Cardiovascular
Targets:
  • Others
  • Kinases
Mechanism of action:
  • Epigenetic

References: we are preparing a list of scientific research reports with L921-0404 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L921-0404?
Check Price and Availability of L921-0404, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L921-0404 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L921-0404
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L921-0404
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L921-0404 available by request