L921-0433 Screening compound: 1-{[5-(4,5-dimethyl-1,3-thiazol-2-yl)-2-methylthiophen-3-yl]sulfonyl}-4-phenyl-1,2,3,6-tetrahydropyridine

L921-0433 Screening compound: 1-{[5-(4,5-dimethyl-1,3-thiazol-2-yl)-2-methylthiophen-3-yl]sulfonyl}-4-phenyl-1,2,3,6-tetrahydropyridine
L921-0433 Screening compound: 1-{[5-(4,5-dimethyl-1,3-thiazol-2-yl)-2-methylthiophen-3-yl]sulfonyl}-4-phenyl-1,2,3,6-tetrahydropyridine alternative view

Chemical Structure Depiction of ChemDiv screening compound L921-0433
1-{[5-(4,5-dimethyl-1,3-thiazol-2-yl)-2-methylthiophen-3-yl]sulfonyl}-4-phenyl-1,2,3,6-tetrahydropyridine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L921-0433

Molecular Formula

C21H22N2O2S3 (C21 H22 N2 O2 S3)

Compound Name

1-{[5-(4,5-dimethyl-1,3-thiazol-2-yl)-2-methylthiophen-3-yl]sulfonyl}-4-phenyl-1,2,3,6-tetrahydropyridine

IUPAC name

1-{[5-(45-dimethyl-13-thiazol-2-yl)-2-methylthiophen-3-yl]sulfonyl}-4-phenyl-1236-tetrahydropyridine

SMILES

Cc1c(C)sc(-c2cc(S(N(CC3)CC=C3c3ccccc3)(=O)=O)c(C)s2)n1

InChI

InChI=1S/C21H22N2O2S3/c1-14-15(2)27-21(22-14)19-13-20(16(3)26-19)28(24,25)23-11-9-18(10-12-23)17-7-5-4-6-8-17/h4-9,13H,10-12H2,1-3H3

InChI Key

WWJQRXTZPSJEDJ-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15137279

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

430.62

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

4

Partition Coefficient, logP

5.679

Distribution Coefficient, logD

5.679

Water Solubility, LogSw

-5.58

Polar Surface Area

43.007

Acid Dissociation Constant (pKa)

28.15

Base Dissociation Constant (pKb)

3.02

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

28.60

L921-0433 in Drug Discovery

Included in Screening Libraries

DGK Inhibitors Library (10558 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Hemic and lymphatic
  • Skin
  • Metabolic
  • Immune system
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with L921-0433 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L921-0433?
Check Price and Availability of L921-0433, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L921-0433 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L921-0433
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L921-0433
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L921-0433 available by request