L921-0471 Screening compound: 5-(4,5-dimethyl-1,3-thiazol-2-yl)-2-methyl-N-[(thiophen-2-yl)methyl]thiophene-3-sulfonamide

L921-0471 Screening compound: 5-(4,5-dimethyl-1,3-thiazol-2-yl)-2-methyl-N-[(thiophen-2-yl)methyl]thiophene-3-sulfonamide
L921-0471 Screening compound: 5-(4,5-dimethyl-1,3-thiazol-2-yl)-2-methyl-N-[(thiophen-2-yl)methyl]thiophene-3-sulfonamide alternative view

Chemical Structure Depiction of ChemDiv screening compound L921-0471
5-(4,5-dimethyl-1,3-thiazol-2-yl)-2-methyl-N-[(thiophen-2-yl)methyl]thiophene-3-sulfonamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L921-0471

Molecular Formula

C15H16N2O2S4 (C15 H16 N2 O2 S4)

Compound Name

5-(4,5-dimethyl-1,3-thiazol-2-yl)-2-methyl-N-[(thiophen-2-yl)methyl]thiophene-3-sulfonamide

IUPAC name

5-(45-dimethyl-13-thiazol-2-yl)-2-methyl-N-[(thiophen-2-yl)methyl]thiophene-3-sulfonamide

SMILES

Cc1c(C)sc(-c2cc(S(NCc3cccs3)(=O)=O)c(C)s2)n1

InChI

InChI=1S/C15H16N2O2S4/c1-9-10(2)22-15(17-9)13-7-14(11(3)21-13)23(18,19)16-8-12-5-4-6-20-12/h4-7,16H,8H2,1-3H3

InChI Key

KQGGZDPVPQZHMT-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15137288

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

384.57

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

4

Partition Coefficient, logP

4.391

Distribution Coefficient, logD

4.388

Water Solubility, LogSw

-4.28

Polar Surface Area

54.344

Acid Dissociation Constant (pKa)

9.48

Base Dissociation Constant (pKb)

3.02

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

26.70

L921-0471 in Drug Discovery

Included in Screening Libraries

Protein Arginine Methyltransferases Library (27925 compounds)

Targeted Diversity Library (40567 compounds)

Akt-Targeted Library (14764 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Metabolic
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
Targets:
  • Others
  • Kinases
Mechanism of action:
  • Epigenetic

References: we are preparing a list of scientific research reports with L921-0471 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L921-0471?
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What is the minimum amount of L921-0471 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L921-0471
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L921-0471
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L921-0471 available by request