L921-0496 Screening compound: 1-{[5-(4,5-dimethyl-1,3-thiazol-2-yl)-2-methylthiophen-3-yl]sulfonyl}-2-methyl-2,3-dihydro-1H-indole

L921-0496 Screening compound: 1-{[5-(4,5-dimethyl-1,3-thiazol-2-yl)-2-methylthiophen-3-yl]sulfonyl}-2-methyl-2,3-dihydro-1H-indole
L921-0496 Screening compound: 1-{[5-(4,5-dimethyl-1,3-thiazol-2-yl)-2-methylthiophen-3-yl]sulfonyl}-2-methyl-2,3-dihydro-1H-indole alternative view

Chemical Structure Depiction of ChemDiv screening compound L921-0496
1-{[5-(4,5-dimethyl-1,3-thiazol-2-yl)-2-methylthiophen-3-yl]sulfonyl}-2-methyl-2,3-dihydro-1H-indole

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L921-0496

Molecular Formula

C19H20N2O2S3 (C19 H20 N2 O2 S3)

Compound Name

1-{[5-(4,5-dimethyl-1,3-thiazol-2-yl)-2-methylthiophen-3-yl]sulfonyl}-2-methyl-2,3-dihydro-1H-indole

IUPAC name

1-{[5-(45-dimethyl-13-thiazol-2-yl)-2-methylthiophen-3-yl]sulfonyl}-2-methyl-23-dihydro-1H-indole

SMILES

CC(Cc1c2cccc1)N2S(c1c(C)sc(-c2nc(C)c(C)s2)c1)(=O)=O

InChI

InChI=1S/C19H20N2O2S3/c1-11-9-15-7-5-6-8-16(15)21(11)26(22,23)18-10-17(24-14(18)4)19-20-12(2)13(3)25-19/h5-8,10-11H,9H2,1-4H3/t11-/m0/s1

InChI Key

PYXHWFTYVDJACQ-NSHDSACASA-N

MDL Number (MFCD)

MFCD15137291

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

404.58

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

3.00

Number of Nitrogen and Oxygen Atoms

4

Partition Coefficient, logP

5.328

Distribution Coefficient, logD

5.328

Water Solubility, LogSw

-5.37

Polar Surface Area

42.802

Acid Dissociation Constant (pKa)

26.25

Base Dissociation Constant (pKb)

3.48

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

31.60

L921-0496 in Drug Discovery

Included in Screening Libraries

Protein Arginine Methyltransferases Library (27925 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Metabolic
Targets:
  • Others
Mechanism of action:
  • Epigenetic

References: we are preparing a list of scientific research reports with L921-0496 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L921-0496?
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What is the minimum amount of L921-0496 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L921-0496
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L921-0496
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L921-0496 available by request