L921-0558 Screening compound: 5-(4,5-dimethyl-1,3-thiazol-2-yl)-2-methyl-N-[2-(4-methylpiperidin-1-yl)ethyl]thiophene-3-sulfonamide

L921-0558 Screening compound: 5-(4,5-dimethyl-1,3-thiazol-2-yl)-2-methyl-N-[2-(4-methylpiperidin-1-yl)ethyl]thiophene-3-sulfonamide
L921-0558 Screening compound: 5-(4,5-dimethyl-1,3-thiazol-2-yl)-2-methyl-N-[2-(4-methylpiperidin-1-yl)ethyl]thiophene-3-sulfonamide alternative view

Chemical Structure Depiction of ChemDiv screening compound L921-0558
5-(4,5-dimethyl-1,3-thiazol-2-yl)-2-methyl-N-[2-(4-methylpiperidin-1-yl)ethyl]thiophene-3-sulfonamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L921-0558

Molecular Formula

C18H27N3O2S3 (C18 H27 N3 O2 S3)

Compound Name

5-(4,5-dimethyl-1,3-thiazol-2-yl)-2-methyl-N-[2-(4-methylpiperidin-1-yl)ethyl]thiophene-3-sulfonamide

IUPAC name

5-(45-dimethyl-13-thiazol-2-yl)-2-methyl-N-[2-(4-methylpiperidin-1-yl)ethyl]thiophene-3-sulfonamide

SMILES

CC1CCN(CCNS(c2c(C)sc(-c3nc(C)c(C)s3)c2)(=O)=O)CC1

InChI

InChI=1S/C18H27N3O2S3/c1-12-5-8-21(9-6-12)10-7-19-26(22,23)17-11-16(24-15(17)4)18-20-13(2)14(3)25-18/h11-12,19H,5-10H2,1-4H3

InChI Key

ULSGJIXWBTVQMO-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27486911

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

413.63

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

4.338

Distribution Coefficient, logD

3.667

Water Solubility, LogSw

-4.11

Polar Surface Area

57.150

Acid Dissociation Constant (pKa)

10.87

Base Dissociation Constant (pKb)

7.97

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

61.10

L921-0558 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Protein Kinases Inhibitors Library (36801 compounds)

SmartTM Library (51161 compounds)

Targeted Diversity Library (40567 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Nervous system
  • Hemic and lymphatic
  • Cardiovascular
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with L921-0558 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L921-0558?
Check Price and Availability of L921-0558, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L921-0558 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L921-0558
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L921-0558
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L921-0558 available by request