L924-1209 Screening compound: 8-({4-[1-(propan-2-yl)-1H-pyrazol-5-yl]thiophen-2-yl}sulfonyl)-1,4-dioxa-8-azaspiro[4.5]decane

L924-1209 Screening compound: 8-({4-[1-(propan-2-yl)-1H-pyrazol-5-yl]thiophen-2-yl}sulfonyl)-1,4-dioxa-8-azaspiro[4.5]decane
L924-1209 Screening compound: 8-({4-[1-(propan-2-yl)-1H-pyrazol-5-yl]thiophen-2-yl}sulfonyl)-1,4-dioxa-8-azaspiro[4.5]decane alternative view

Chemical Structure Depiction of ChemDiv screening compound L924-1209
8-({4-[1-(propan-2-yl)-1H-pyrazol-5-yl]thiophen-2-yl}sulfonyl)-1,4-dioxa-8-azaspiro[4.5]decane

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L924-1209

Molecular Formula

C17H23N3O4S2 (C17 H23 N3 O4 S2)

Compound Name

8-({4-[1-(propan-2-yl)-1H-pyrazol-5-yl]thiophen-2-yl}sulfonyl)-1,4-dioxa-8-azaspiro[4.5]decane

IUPAC name

8-({4-[1-(propan-2-yl)-1H-pyrazol-5-yl]thiophen-2-yl}sulfonyl)-14-dioxa-8-azaspiro[4.5]decane

SMILES

CC(C)n1nccc1-c1csc(S(N(CC2)CCC22OCCO2)(=O)=O)c1

InChI

InChI=1S/C17H23N3O4S2/c1-13(2)20-15(3-6-18-20)14-11-16(25-12-14)26(21,22)19-7-4-17(5-8-19)23-9-10-24-17/h3,6,11-13H,4-5,7-10H2,1-2H3

InChI Key

JXIOUJQEIAIKRX-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27487193

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

397.52

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

2.310

Distribution Coefficient, logD

2.310

Water Solubility, LogSw

-2.62

Polar Surface Area

60.966

Acid Dissociation Constant (pKa)

27.46

Base Dissociation Constant (pKb)

3.04

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

58.80

L924-1209 in Drug Discovery

Included in Screening Libraries

Anticancer Library (62698 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

SmartTM Library (51161 compounds)

Targeted Diversity Library (40567 compounds)

Akt-Targeted Library (14764 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with L924-1209 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L924-1209?
Check Price and Availability of L924-1209, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L924-1209 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L924-1209
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L924-1209
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L924-1209 available by request