L926-0123 Screening compound: 2-(2,4-dimethylphenyl)-5-{[3-(4-fluorophenyl)-1,2,4-oxadiazol-5-yl]methyl}-4H,5H-pyrazolo[1,5-d][1,2,4]triazin-4-one

L926-0123 Screening compound: 2-(2,4-dimethylphenyl)-5-{[3-(4-fluorophenyl)-1,2,4-oxadiazol-5-yl]methyl}-4H,5H-pyrazolo[1,5-d][1,2,4]triazin-4-one
L926-0123 Screening compound: 2-(2,4-dimethylphenyl)-5-{[3-(4-fluorophenyl)-1,2,4-oxadiazol-5-yl]methyl}-4H,5H-pyrazolo[1,5-d][1,2,4]triazin-4-one alternative view

Chemical Structure Depiction of ChemDiv screening compound L926-0123
2-(2,4-dimethylphenyl)-5-{[3-(4-fluorophenyl)-1,2,4-oxadiazol-5-yl]methyl}-4H,5H-pyrazolo[1,5-d][1,2,4]triazin-4-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L926-0123

Molecular Formula

C22H17FN6O2 (C22 H17 FN6 O2)

Compound Name

2-(2,4-dimethylphenyl)-5-{[3-(4-fluorophenyl)-1,2,4-oxadiazol-5-yl]methyl}-4H,5H-pyrazolo[1,5-d][1,2,4]triazin-4-one

IUPAC name

2-(24-dimethylphenyl)-5-{[3-(4-fluorophenyl)-124-oxadiazol-5-yl]methyl}-4H5H-pyrazolo[15-d][124]triazin-4-one

SMILES

Cc(cc1)cc(C)c1-c1nn(C=NN(Cc2nc(-c(cc3)ccc3F)no2)C2=O)c2c1

InChI

InChI=1S/C22H17FN6O2/c1-13-3-8-17(14(2)9-13)18-10-19-22(30)28(24-12-29(19)26-18)11-20-25-21(27-31-20)15-4-6-16(23)7-5-15/h3-10,12H,11H2,1-2H3

InChI Key

HIACWJWKFKJGAP-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27487326

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

416.41

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

4.107

Distribution Coefficient, logD

4.107

Water Solubility, LogSw

-4.25

Polar Surface Area

73.488

Acid Dissociation Constant (pKa)

23.81

Base Dissociation Constant (pKb)

3.06

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

13.60

L926-0123 in Drug Discovery

Included in Screening Libraries

Anticancer Library (62698 compounds)

Antiviral Library (67538 compounds)

CNS Targets (44014 compounds)

Immunological Library (6760 compounds)

SmartTM Library (51161 compounds)

Neuropeptide S Library (2850 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Antiviral
  • Infections
  • Immune system
  • Nervous system
  • Immune system
  • Digestive system
  • Nervous system
Targets:
  • GPCR
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with L926-0123 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L926-0123?
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What is the minimum amount of L926-0123 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L926-0123
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L926-0123
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L926-0123 available by request