L926-0349 Screening compound: 2-(thiophen-2-yl)-5-({3-[3-(trifluoromethyl)phenyl]-1,2,4-oxadiazol-5-yl}methyl)-4H,5H-pyrazolo[1,5-d][1,2,4]triazin-4-one

L926-0349 Screening compound: 2-(thiophen-2-yl)-5-({3-[3-(trifluoromethyl)phenyl]-1,2,4-oxadiazol-5-yl}methyl)-4H,5H-pyrazolo[1,5-d][1,2,4]triazin-4-one
L926-0349 Screening compound: 2-(thiophen-2-yl)-5-({3-[3-(trifluoromethyl)phenyl]-1,2,4-oxadiazol-5-yl}methyl)-4H,5H-pyrazolo[1,5-d][1,2,4]triazin-4-one alternative view

Chemical Structure Depiction of ChemDiv screening compound L926-0349
2-(thiophen-2-yl)-5-({3-[3-(trifluoromethyl)phenyl]-1,2,4-oxadiazol-5-yl}methyl)-4H,5H-pyrazolo[1,5-d][1,2,4]triazin-4-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L926-0349

Molecular Formula

C19H11F3N6O2S (C19 H11 F3 N6 O2 S)

Compound Name

2-(thiophen-2-yl)-5-({3-[3-(trifluoromethyl)phenyl]-1,2,4-oxadiazol-5-yl}methyl)-4H,5H-pyrazolo[1,5-d][1,2,4]triazin-4-one

IUPAC name

2-(thiophen-2-yl)-5-({3-[3-(trifluoromethyl)phenyl]-124-oxadiazol-5-yl}methyl)-4H5H-pyrazolo[15-d][124]triazin-4-one

SMILES

O=C(c1c2)N(Cc3nc(-c4cc(C(F)(F)F)ccc4)no3)N=Cn1nc2-c1cccs1

InChI

InChI=1S/C19H11F3N6O2S/c20-19(21,22)12-4-1-3-11(7-12)17-24-16(30-26-17)9-27-18(29)14-8-13(15-5-2-6-31-15)25-28(14)10-23-27/h1-8,10H,9H2

InChI Key

QKLYYSKSYBLHQE-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27487351

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

444.4

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

3.849

Distribution Coefficient, logD

3.849

Water Solubility, LogSw

-4.22

Polar Surface Area

74.507

Acid Dissociation Constant (pKa)

23.81

Base Dissociation Constant (pKb)

2.62

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

10.50

L926-0349 in Drug Discovery

Included in Screening Libraries

Anti-Inflammatory Library (24602 compounds)

Anticancer Library (62698 compounds)

Antiviral Library (67538 compounds)

SmartTM Library (51161 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Immune system
  • Cancer
  • Antiviral
  • Infections
  • Immune system

References: we are preparing a list of scientific research reports with L926-0349 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L926-0349?
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What is the minimum amount of L926-0349 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L926-0349
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L926-0349
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L926-0349 available by request