L927-0194 Screening compound: 1-{[3-(2-methoxyphenyl)-1,2,4-oxadiazol-5-yl]methyl}-3-(4-methylphenyl)-1H,2H,3H,4H-thieno[3,2-d]pyrimidine-2,4-dione

L927-0194 Screening compound: 1-{[3-(2-methoxyphenyl)-1,2,4-oxadiazol-5-yl]methyl}-3-(4-methylphenyl)-1H,2H,3H,4H-thieno[3,2-d]pyrimidine-2,4-dione
L927-0194 Screening compound: 1-{[3-(2-methoxyphenyl)-1,2,4-oxadiazol-5-yl]methyl}-3-(4-methylphenyl)-1H,2H,3H,4H-thieno[3,2-d]pyrimidine-2,4-dione alternative view

Chemical Structure Depiction of ChemDiv screening compound L927-0194
1-{[3-(2-methoxyphenyl)-1,2,4-oxadiazol-5-yl]methyl}-3-(4-methylphenyl)-1H,2H,3H,4H-thieno[3,2-d]pyrimidine-2,4-dione

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L927-0194

Molecular Formula

C23H18N4O4S (C23 H18 N4 O4 S)

Compound Name

1-{[3-(2-methoxyphenyl)-1,2,4-oxadiazol-5-yl]methyl}-3-(4-methylphenyl)-1H,2H,3H,4H-thieno[3,2-d]pyrimidine-2,4-dione

IUPAC name

1-{[3-(2-methoxyphenyl)-124-oxadiazol-5-yl]methyl}-3-(4-methylphenyl)-1H2H3H4H-thieno[32-d]pyrimidine-24-dione

SMILES

Cc(cc1)ccc1N(C(c(scc1)c1N1Cc2nc(-c(cccc3)c3OC)no2)=O)C1=O

InChI

InChI=1S/C23H18N4O4S/c1-14-7-9-15(10-8-14)27-22(28)20-17(11-12-32-20)26(23(27)29)13-19-24-21(25-31-19)16-5-3-4-6-18(16)30-2/h3-12H,13H2,1-2H3

InChI Key

ZZWUGKSUFBJMQU-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD16635312

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

446.49

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

4.188

Distribution Coefficient, logD

4.188

Water Solubility, LogSw

-4.49

Polar Surface Area

70.647

Acid Dissociation Constant (pKa)

28.80

Base Dissociation Constant (pKb)

-3.46

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

13.00

L927-0194 in Drug Discovery

Included in Screening Libraries

Anticancer Library (62698 compounds)

SmartTM Library (51161 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer

References: we are preparing a list of scientific research reports with L927-0194 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L927-0194?
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What is the minimum amount of L927-0194 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L927-0194
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L927-0194
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L927-0194 available by request