L927-0276 Screening compound: 3-[(2H-1,3-benzodioxol-5-yl)methyl]-1-{[3-(2-methylphenyl)-1,2,4-oxadiazol-5-yl]methyl}-1H,2H,3H,4H-thieno[3,2-d]pyrimidine-2,4-dione

L927-0276 Screening compound: 3-[(2H-1,3-benzodioxol-5-yl)methyl]-1-{[3-(2-methylphenyl)-1,2,4-oxadiazol-5-yl]methyl}-1H,2H,3H,4H-thieno[3,2-d]pyrimidine-2,4-dione
L927-0276 Screening compound: 3-[(2H-1,3-benzodioxol-5-yl)methyl]-1-{[3-(2-methylphenyl)-1,2,4-oxadiazol-5-yl]methyl}-1H,2H,3H,4H-thieno[3,2-d]pyrimidine-2,4-dione alternative view

Chemical Structure Depiction of ChemDiv screening compound L927-0276
3-[(2H-1,3-benzodioxol-5-yl)methyl]-1-{[3-(2-methylphenyl)-1,2,4-oxadiazol-5-yl]methyl}-1H,2H,3H,4H-thieno[3,2-d]pyrimidine-2,4-dione

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L927-0276

Molecular Formula

C24H18N4O5S (C24 H18 N4 O5 S)

Compound Name

3-[(2H-1,3-benzodioxol-5-yl)methyl]-1-{[3-(2-methylphenyl)-1,2,4-oxadiazol-5-yl]methyl}-1H,2H,3H,4H-thieno[3,2-d]pyrimidine-2,4-dione

IUPAC name

3-[(2H-13-benzodioxol-5-yl)methyl]-1-{[3-(2-methylphenyl)-124-oxadiazol-5-yl]methyl}-1H2H3H4H-thieno[32-d]pyrimidine-24-dione

SMILES

Cc(cccc1)c1-c1noc(CN(c2c(C(N3Cc(cc4)cc5c4OCO5)=O)scc2)C3=O)n1

InChI

InChI=1S/C24H18N4O5S/c1-14-4-2-3-5-16(14)22-25-20(33-26-22)12-27-17-8-9-34-21(17)23(29)28(24(27)30)11-15-6-7-18-19(10-15)32-13-31-18/h2-10H,11-13H2,1H3

InChI Key

IUXOGEXJRRLCMX-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD16635559

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

474.5

Hydrogen Bond Acceptors Count

9.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

9

Partition Coefficient, logP

4.823

Distribution Coefficient, logD

4.823

Water Solubility, LogSw

-4.61

Polar Surface Area

80.744

Acid Dissociation Constant (pKa)

28.18

Base Dissociation Constant (pKb)

-6.32

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

16.70

L927-0276 in Drug Discovery

Included in Screening Libraries

Anticancer Library (62698 compounds)

Immunological Library (6760 compounds)

SmartTM Library (51161 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Immune system

References: we are preparing a list of scientific research reports with L927-0276 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L927-0276?
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What is the minimum amount of L927-0276 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L927-0276
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L927-0276
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L927-0276 available by request