L928-0055 Screening compound: 1-[1]benzofuro[3,2-d]pyrimidin-4-yl-N~4~-[2-(1H-indol-3-yl)ethyl]-4-piperidinecarboxamide

L928-0055 Screening compound: 1-[1]benzofuro[3,2-d]pyrimidin-4-yl-N~4~-[2-(1H-indol-3-yl)ethyl]-4-piperidinecarboxamide
L928-0055 Screening compound: 1-[1]benzofuro[3,2-d]pyrimidin-4-yl-N~4~-[2-(1H-indol-3-yl)ethyl]-4-piperidinecarboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound L928-0055
1-[1]benzofuro[3,2-d]pyrimidin-4-yl-N~4~-[2-(1H-indol-3-yl)ethyl]-4-piperidinecarboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L928-0055

Molecular Formula

C26H25N5O2 (C26 H25 N5 O2)

Compound Name

1-[1]benzofuro[3,2-d]pyrimidin-4-yl-N~4~-[2-(1H-indol-3-yl)ethyl]-4-piperidinecarboxamide

IUPAC name

N-[2-(1H-indol-3-yl)ethyl]-1-{8-oxa-35-diazatricyclo[7.4.0.0^{27}]trideca-1(9)2(7)351012-hexaen-6-yl}piperidine-4-carboxamide

SMILES

O=C(C(CC1)CCN1c1ncnc2c1oc1c2cccc1)NCCc1c[nH]c2c1cccc2

InChI

InChI=1S/C26H25N5O2/c32-26(27-12-9-18-15-28-21-7-3-1-5-19(18)21)17-10-13-31(14-11-17)25-24-23(29-16-30-25)20-6-2-4-8-22(20)33-24/h1-8,15-17,28H,9-14H2,(H,27,32)

InChI Key

KLDPBKUPBSLCSQ-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD20750353

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

439.52

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

4.358

Distribution Coefficient, logD

4.332

Water Solubility, LogSw

-4.26

Polar Surface Area

66.464

Acid Dissociation Constant (pKa)

13.87

Base Dissociation Constant (pKb)

6.20

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

26.90

L928-0055 in Drug Discovery

Included in Screening Libraries

3D-Pharmacophore Based Diversity Library (49813 compounds)

CNS Targets (44014 compounds)

Indole Derivatives (10091 compounds)

Macl-GPIb alpha Interaction Library (22969 compounds)

SmartTM Library (51161 compounds)

Akt-Targeted Library (14764 compounds)

Inhibitors of beta-Catenin Signaling (7445 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Nervous system
  • Hemic and lymphatic
  • Cardiovascular
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
Structure:
  • Cyclic compounds
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with L928-0055 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L928-0055?
Check Price and Availability of L928-0055, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L928-0055 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L928-0055
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L928-0055
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L928-0055 available by request