L928-0145 Screening compound: (1-[1]benzofuro[3,2-d]pyrimidin-4-yl-4-piperidyl)(4-benzylpiperidino)methanone

L928-0145 Screening compound: (1-[1]benzofuro[3,2-d]pyrimidin-4-yl-4-piperidyl)(4-benzylpiperidino)methanone
L928-0145 Screening compound: (1-[1]benzofuro[3,2-d]pyrimidin-4-yl-4-piperidyl)(4-benzylpiperidino)methanone alternative view

Chemical Structure Depiction of ChemDiv screening compound L928-0145
(1-[1]benzofuro[3,2-d]pyrimidin-4-yl-4-piperidyl)(4-benzylpiperidino)methanone

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L928-0145

Molecular Formula

C28H30N4O2 (C28 H30 N4 O2)

Compound Name

(1-[1]benzofuro[3,2-d]pyrimidin-4-yl-4-piperidyl)(4-benzylpiperidino)methanone

IUPAC name

6-[4-(4-benzylpiperidine-1-carbonyl)piperidin-1-yl]-8-oxa-35-diazatricyclo[7.4.0.0^{27}]trideca-1(9)2(7)351012-hexaene

SMILES

O=C(C(CC1)CCN1c1ncnc2c1oc1c2cccc1)N1CCC(Cc2ccccc2)CC1

InChI

InChI=1S/C28H30N4O2/c33-28(32-14-10-21(11-15-32)18-20-6-2-1-3-7-20)22-12-16-31(17-13-22)27-26-25(29-19-30-27)23-8-4-5-9-24(23)34-26/h1-9,19,21-22H,10-18H2

InChI Key

VZSRYLIYNHHBRA-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD20750363

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

454.57

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

5.717

Distribution Coefficient, logD

5.685

Water Solubility, LogSw

-6.22

Polar Surface Area

48.715

Acid Dissociation Constant (pKa)

21.64

Base Dissociation Constant (pKb)

6.28

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

39.30

L928-0145 in Drug Discovery

Included in Screening Libraries

3D-Pharmacophore Based Diversity Library (49813 compounds)

CNS Targets (44014 compounds)

GPCR Targeted Library (31838 compounds)

Macl-GPIb alpha Interaction Library (22969 compounds)

SmartTM Library (51161 compounds)

Targeted Diversity Library (40567 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Nervous system
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
  • Hemic and lymphatic
  • Cardiovascular
Targets:
  • GPCR
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with L928-0145 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L928-0145?
Check Price and Availability of L928-0145, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L928-0145 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L928-0145
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L928-0145
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L928-0145 available by request