L928-0153 Screening compound: (1-[1]benzofuro[3,2-d]pyrimidin-4-yl-4-piperidyl)[4-(2-chlorophenyl)piperazino]methanone

L928-0153 Screening compound: (1-[1]benzofuro[3,2-d]pyrimidin-4-yl-4-piperidyl)[4-(2-chlorophenyl)piperazino]methanone
L928-0153 Screening compound: (1-[1]benzofuro[3,2-d]pyrimidin-4-yl-4-piperidyl)[4-(2-chlorophenyl)piperazino]methanone alternative view

Chemical Structure Depiction of ChemDiv screening compound L928-0153
(1-[1]benzofuro[3,2-d]pyrimidin-4-yl-4-piperidyl)[4-(2-chlorophenyl)piperazino]methanone

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L928-0153

Molecular Formula

C26H26ClN5O2 (C26 H26 ClN5 O2)

Compound Name

(1-[1]benzofuro[3,2-d]pyrimidin-4-yl-4-piperidyl)[4-(2-chlorophenyl)piperazino]methanone

IUPAC name

6-{4-[4-(2-chlorophenyl)piperazine-1-carbonyl]piperidin-1-yl}-8-oxa-35-diazatricyclo[7.4.0.0^{27}]trideca-1(9)2(7)351012-hexaene

SMILES

O=C(C(CC1)CCN1c1ncnc2c1oc1c2cccc1)N(CC1)CCN1c(cccc1)c1Cl

InChI

InChI=1S/C26H26ClN5O2/c27-20-6-2-3-7-21(20)30-13-15-32(16-14-30)26(33)18-9-11-31(12-10-18)25-24-23(28-17-29-25)19-5-1-4-8-22(19)34-24/h1-8,17-18H,9-16H2

InChI Key

YCPUCSJMUDNGGG-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD20750365

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

475.98

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

5.056

Distribution Coefficient, logD

5.024

Water Solubility, LogSw

-5.20

Polar Surface Area

51.946

Acid Dissociation Constant (pKa)

21.64

Base Dissociation Constant (pKb)

6.28

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

34.60

L928-0153 in Drug Discovery

Included in Screening Libraries

3D-Pharmacophore Based Diversity Library (49813 compounds)

Anti-Inflammatory Library (24602 compounds)

GPCR Targeted Library (31838 compounds)

Macl-GPIb alpha Interaction Library (22969 compounds)

SmartTM Library (51161 compounds)

Targeted Diversity Library (40567 compounds)

New Agro Library (44492 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Immune system
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
  • Hemic and lymphatic
  • Cardiovascular
Targets:
  • GPCR
Mechanism of action:
  • Receptor's ligands
Agro:
  • Agro

References: we are preparing a list of scientific research reports with L928-0153 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L928-0153?
Check Price and Availability of L928-0153, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L928-0153 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L928-0153
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L928-0153
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L928-0153 available by request