L928-0414 Screening compound: 1-[1]benzofuro[3,2-d]pyrimidin-4-yl-N~3~-(2-chloro-4-fluorobenzyl)-3-piperidinecarboxamide

L928-0414 Screening compound: 1-[1]benzofuro[3,2-d]pyrimidin-4-yl-N~3~-(2-chloro-4-fluorobenzyl)-3-piperidinecarboxamide
L928-0414 Screening compound: 1-[1]benzofuro[3,2-d]pyrimidin-4-yl-N~3~-(2-chloro-4-fluorobenzyl)-3-piperidinecarboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound L928-0414
1-[1]benzofuro[3,2-d]pyrimidin-4-yl-N~3~-(2-chloro-4-fluorobenzyl)-3-piperidinecarboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L928-0414

Molecular Formula

C23H20ClFN4O2 (C23 H20 ClFN4 O2)

Compound Name

1-[1]benzofuro[3,2-d]pyrimidin-4-yl-N~3~-(2-chloro-4-fluorobenzyl)-3-piperidinecarboxamide

IUPAC name

N-[(2-chloro-4-fluorophenyl)methyl]-1-{8-oxa-35-diazatricyclo[7.4.0.0^{27}]trideca-1(9)2(7)351012-hexaen-6-yl}piperidine-3-carboxamide

SMILES

O=C(C(CCC1)CN1c1ncnc2c1oc1c2cccc1)NCc(ccc(F)c1)c1Cl

InChI

InChI=1S/C23H20ClFN4O2/c24-18-10-16(25)8-7-14(18)11-26-23(30)15-4-3-9-29(12-15)22-21-20(27-13-28-22)17-5-1-2-6-19(17)31-21/h1-2,5-8,10,13,15H,3-4,9,11-12H2,(H,26,30)/t15-/m0/s1

InChI Key

GWWWNHZZKHJFPK-HNNXBMFYSA-N

MDL Number (MFCD)

MFCD20750401

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

438.89

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

4.701

Distribution Coefficient, logD

4.691

Water Solubility, LogSw

-5.00

Polar Surface Area

56.685

Acid Dissociation Constant (pKa)

11.94

Base Dissociation Constant (pKb)

5.78

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

26.10

L928-0414 in Drug Discovery

Included in Screening Libraries

Angiogenesis library (14822 compounds)

CNS Targets (44014 compounds)

SmartTM Library (51161 compounds)

Targeted Diversity Library (40567 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Nervous system

References: we are preparing a list of scientific research reports with L928-0414 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L928-0414?
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What is the minimum amount of L928-0414 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L928-0414
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L928-0414
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L928-0414 available by request