L928-0467 Screening compound: 1-[1]benzofuro[3,2-d]pyrimidin-4-yl-N~3~-(1-benzyl-4-piperidyl)-3-piperidinecarboxamide

L928-0467 Screening compound: 1-[1]benzofuro[3,2-d]pyrimidin-4-yl-N~3~-(1-benzyl-4-piperidyl)-3-piperidinecarboxamide
L928-0467 Screening compound: 1-[1]benzofuro[3,2-d]pyrimidin-4-yl-N~3~-(1-benzyl-4-piperidyl)-3-piperidinecarboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound L928-0467
1-[1]benzofuro[3,2-d]pyrimidin-4-yl-N~3~-(1-benzyl-4-piperidyl)-3-piperidinecarboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L928-0467

Molecular Formula

C28H31N5O2 (C28 H31 N5 O2)

Compound Name

1-[1]benzofuro[3,2-d]pyrimidin-4-yl-N~3~-(1-benzyl-4-piperidyl)-3-piperidinecarboxamide

IUPAC name

N-(1-benzylpiperidin-4-yl)-1-{8-oxa-35-diazatricyclo[7.4.0.0^{27}]trideca-1(9)2(7)351012-hexaen-6-yl}piperidine-3-carboxamide

SMILES

O=C(C(CCC1)CN1c1ncnc2c1oc1c2cccc1)NC1CCN(Cc2ccccc2)CC1

InChI

InChI=1S/C28H31N5O2/c34-28(31-22-12-15-32(16-13-22)17-20-7-2-1-3-8-20)21-9-6-14-33(18-21)27-26-25(29-19-30-27)23-10-4-5-11-24(23)35-26/h1-5,7-8,10-11,19,21-22H,6,9,12-18H2,(H,31,34)/t21-/m0/s1

InChI Key

DXSVBCFYBMNZQI-NRFANRHFSA-N

MDL Number (MFCD)

MFCD20750413

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

469.59

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

4.033

Distribution Coefficient, logD

2.475

Water Solubility, LogSw

-4.13

Polar Surface Area

59.951

Acid Dissociation Constant (pKa)

15.49

Base Dissociation Constant (pKb)

8.95

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

39.30

L928-0467 in Drug Discovery

Included in Screening Libraries

GPCR Targeted Library (31838 compounds)

SmartTM Library (51161 compounds)

Targeted Diversity Library (40567 compounds)

Anti-HIV1 Library (19540 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
  • Antiviral
  • Infections
  • Immune system
Targets:
  • GPCR
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with L928-0467 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L928-0467?
Check Price and Availability of L928-0467, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L928-0467 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L928-0467
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L928-0467
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L928-0467 available by request