L933-0325 Screening compound: 1-(3-methoxyphenyl)-3-(1-{4-[(4-methylphenyl)methyl]-3-oxo-3H,4H-pyrido[2,3-b]pyrazin-2-yl}piperidin-4-yl)urea

L933-0325 Screening compound: 1-(3-methoxyphenyl)-3-(1-{4-[(4-methylphenyl)methyl]-3-oxo-3H,4H-pyrido[2,3-b]pyrazin-2-yl}piperidin-4-yl)urea
L933-0325 Screening compound: 1-(3-methoxyphenyl)-3-(1-{4-[(4-methylphenyl)methyl]-3-oxo-3H,4H-pyrido[2,3-b]pyrazin-2-yl}piperidin-4-yl)urea alternative view

Chemical Structure Depiction of ChemDiv screening compound L933-0325
1-(3-methoxyphenyl)-3-(1-{4-[(4-methylphenyl)methyl]-3-oxo-3H,4H-pyrido[2,3-b]pyrazin-2-yl}piperidin-4-yl)urea

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L933-0325

Molecular Formula

C28H30N6O3 (C28 H30 N6 O3)

Compound Name

1-(3-methoxyphenyl)-3-(1-{4-[(4-methylphenyl)methyl]-3-oxo-3H,4H-pyrido[2,3-b]pyrazin-2-yl}piperidin-4-yl)urea

IUPAC name

1-(3-methoxyphenyl)-3-(1-{4-[(4-methylphenyl)methyl]-3-oxo-3H4H-pyrido[23-b]pyrazin-2-yl}piperidin-4-yl)urea

SMILES

Cc1ccc(CN(c2ncccc2N=C2N(CC3)CCC3NC(Nc3cc(OC)ccc3)=O)C2=O)cc1

InChI

InChI=1S/C28H30N6O3/c1-19-8-10-20(11-9-19)18-34-25-24(7-4-14-29-25)32-26(27(34)35)33-15-12-21(13-16-33)30-28(36)31-22-5-3-6-23(17-22)37-2/h3-11,14,17,21H,12-13,15-16,18H2,1-2H3,(H2,30,31,36)

InChI Key

MSCXAKXCVGYKHW-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27488173

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

498.58

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

9

Partition Coefficient, logP

3.980

Distribution Coefficient, logD

3.980

Water Solubility, LogSw

-4.03

Polar Surface Area

77.253

Acid Dissociation Constant (pKa)

13.29

Base Dissociation Constant (pKb)

3.04

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

28.60

L933-0325 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Chelators targeting matrix metalloproteinases library (8930 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Cardiovascular
Targets:
  • Proteases

References: we are preparing a list of scientific research reports with L933-0325 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L933-0325?
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What is the minimum amount of L933-0325 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L933-0325
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L933-0325
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L933-0325 available by request