L933-0359 Screening compound: 1-(4-acetylphenyl)-3-(1-{4-benzyl-3-oxo-3H,4H-pyrido[2,3-b]pyrazin-2-yl}piperidin-4-yl)urea

L933-0359 Screening compound: 1-(4-acetylphenyl)-3-(1-{4-benzyl-3-oxo-3H,4H-pyrido[2,3-b]pyrazin-2-yl}piperidin-4-yl)urea
L933-0359 Screening compound: 1-(4-acetylphenyl)-3-(1-{4-benzyl-3-oxo-3H,4H-pyrido[2,3-b]pyrazin-2-yl}piperidin-4-yl)urea alternative view

Chemical Structure Depiction of ChemDiv screening compound L933-0359
1-(4-acetylphenyl)-3-(1-{4-benzyl-3-oxo-3H,4H-pyrido[2,3-b]pyrazin-2-yl}piperidin-4-yl)urea

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L933-0359

Molecular Formula

C28H28N6O3 (C28 H28 N6 O3)

Compound Name

1-(4-acetylphenyl)-3-(1-{4-benzyl-3-oxo-3H,4H-pyrido[2,3-b]pyrazin-2-yl}piperidin-4-yl)urea

IUPAC name

1-(4-acetylphenyl)-3-(1-{4-benzyl-3-oxo-3H4H-pyrido[23-b]pyrazin-2-yl}piperidin-4-yl)urea

SMILES

CC(c(cc1)ccc1NC(NC(CC1)CCN1C1=Nc2cccnc2N(Cc2ccccc2)C1=O)=O)=O

InChI

InChI=1S/C28H28N6O3/c1-19(35)21-9-11-22(12-10-21)30-28(37)31-23-13-16-33(17-14-23)26-27(36)34(18-20-6-3-2-4-7-20)25-24(32-26)8-5-15-29-25/h2-12,15,23H,13-14,16-18H2,1H3,(H2,30,31,37)

InChI Key

SZWIDGGZRKDGRM-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27488196

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

496.57

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

9

Partition Coefficient, logP

3.033

Distribution Coefficient, logD

3.033

Water Solubility, LogSw

-3.38

Polar Surface Area

83.536

Acid Dissociation Constant (pKa)

12.17

Base Dissociation Constant (pKb)

3.04

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

25.00

L933-0359 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Chelators targeting matrix metalloproteinases library (8930 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Cardiovascular
Targets:
  • Proteases

References: we are preparing a list of scientific research reports with L933-0359 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L933-0359?
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What is the minimum amount of L933-0359 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L933-0359
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L933-0359
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L933-0359 available by request