L933-0439 Screening compound: methyl 2-[({1-[3-oxo-4-(prop-2-en-1-yl)-3H,4H-pyrido[2,3-b]pyrazin-2-yl]piperidin-4-yl}carbamoyl)amino]-3-phenylpropanoate

L933-0439 Screening compound: methyl 2-[({1-[3-oxo-4-(prop-2-en-1-yl)-3H,4H-pyrido[2,3-b]pyrazin-2-yl]piperidin-4-yl}carbamoyl)amino]-3-phenylpropanoate
L933-0439 Screening compound: methyl 2-[({1-[3-oxo-4-(prop-2-en-1-yl)-3H,4H-pyrido[2,3-b]pyrazin-2-yl]piperidin-4-yl}carbamoyl)amino]-3-phenylpropanoate alternative view

Chemical Structure Depiction of ChemDiv screening compound L933-0439
methyl 2-[({1-[3-oxo-4-(prop-2-en-1-yl)-3H,4H-pyrido[2,3-b]pyrazin-2-yl]piperidin-4-yl}carbamoyl)amino]-3-phenylpropanoate

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L933-0439

Molecular Formula

C26H30N6O4 (C26 H30 N6 O4)

Compound Name

methyl 2-[({1-[3-oxo-4-(prop-2-en-1-yl)-3H,4H-pyrido[2,3-b]pyrazin-2-yl]piperidin-4-yl}carbamoyl)amino]-3-phenylpropanoate

IUPAC name

methyl 2-[({1-[3-oxo-4-(prop-2-en-1-yl)-3H4H-pyrido[23-b]pyrazin-2-yl]piperidin-4-yl}carbamoyl)amino]-3-phenylpropanoate

SMILES

COC(C(Cc1ccccc1)NC(NC(CC1)CCN1C1=Nc2cccnc2N(CC=C)C1=O)=O)=O

InChI

InChI=1S/C26H30N6O4/c1-3-14-32-22-20(10-7-13-27-22)29-23(24(32)33)31-15-11-19(12-16-31)28-26(35)30-21(25(34)36-2)17-18-8-5-4-6-9-18/h3-10,13,19,21H,1,11-12,14-17H2,2H3,(H2,28,30,35)/t21-/m0/s1

InChI Key

TXSPAQDROCSTEB-NRFANRHFSA-N

MDL Number (MFCD)

MFCD27488247

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

490.56

Hydrogen Bond Acceptors Count

9.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

11.00

Number of Nitrogen and Oxygen Atoms

10

Partition Coefficient, logP

1.803

Distribution Coefficient, logD

1.803

Water Solubility, LogSw

-1.94

Polar Surface Area

92.085

Acid Dissociation Constant (pKa)

14.78

Base Dissociation Constant (pKb)

4.12

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

34.60

L933-0439 in Drug Discovery

Included in Screening Libraries

Antiviral Library (67538 compounds)

Chelators targeting matrix metalloproteinases library (8930 compounds)

Eccentric PPI Library (11937 compounds)

Integrin Receptors Targeted library (1715 compounds)

KRAS-Targeted Library (16000 compounds)

Macl-GPIb alpha Interaction Library (22969 compounds)

Protein-Protein Interaction Library (218420 compounds)

Anti-HIV1 Library (19540 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Antiviral
  • Infections
  • Immune system
  • Cancer
  • Digestive system
  • Cardiovascular
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Nervous system
  • Hemic and lymphatic
  • Cardiovascular
  • Immune system
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Hemic and lymphatic
  • Cardiovascular
  • Antiviral
  • Infections
  • Immune system
Targets:
  • Proteases
  • Others
  • Kinases
Mechanism of action:
  • PPI modulators
  • PPI modulators
Structure:
  • Cyclic compounds

References: we are preparing a list of scientific research reports with L933-0439 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L933-0439?
Check Price and Availability of L933-0439, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L933-0439 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L933-0439
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L933-0439
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L933-0439 available by request