L933-0457 Screening compound: 1-(4-ethoxyphenyl)-3-{1-[3-oxo-4-(prop-2-en-1-yl)-3H,4H-pyrido[2,3-b]pyrazin-2-yl]piperidin-4-yl}urea

L933-0457 Screening compound: 1-(4-ethoxyphenyl)-3-{1-[3-oxo-4-(prop-2-en-1-yl)-3H,4H-pyrido[2,3-b]pyrazin-2-yl]piperidin-4-yl}urea
L933-0457 Screening compound: 1-(4-ethoxyphenyl)-3-{1-[3-oxo-4-(prop-2-en-1-yl)-3H,4H-pyrido[2,3-b]pyrazin-2-yl]piperidin-4-yl}urea alternative view

Chemical Structure Depiction of ChemDiv screening compound L933-0457
1-(4-ethoxyphenyl)-3-{1-[3-oxo-4-(prop-2-en-1-yl)-3H,4H-pyrido[2,3-b]pyrazin-2-yl]piperidin-4-yl}urea

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L933-0457

Molecular Formula

C24H28N6O3 (C24 H28 N6 O3)

Compound Name

1-(4-ethoxyphenyl)-3-{1-[3-oxo-4-(prop-2-en-1-yl)-3H,4H-pyrido[2,3-b]pyrazin-2-yl]piperidin-4-yl}urea

IUPAC name

1-(4-ethoxyphenyl)-3-{1-[3-oxo-4-(prop-2-en-1-yl)-3H4H-pyrido[23-b]pyrazin-2-yl]piperidin-4-yl}urea

SMILES

CCOc(cc1)ccc1NC(NC(CC1)CCN1C1=Nc2cccnc2N(CC=C)C1=O)=O

InChI

InChI=1S/C24H28N6O3/c1-3-14-30-21-20(6-5-13-25-21)28-22(23(30)31)29-15-11-18(12-16-29)27-24(32)26-17-7-9-19(10-8-17)33-4-2/h3,5-10,13,18H,1,4,11-12,14-16H2,2H3,(H2,26,27,32)

InChI Key

UHARYLYWVWLZOE-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27488257

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

448.52

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

9.00

Number of Nitrogen and Oxygen Atoms

9

Partition Coefficient, logP

2.743

Distribution Coefficient, logD

2.743

Water Solubility, LogSw

-3.23

Polar Surface Area

77.083

Acid Dissociation Constant (pKa)

13.94

Base Dissociation Constant (pKb)

4.12

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

33.30

L933-0457 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Chelators targeting matrix metalloproteinases library (8930 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Cardiovascular
Targets:
  • Proteases

References: we are preparing a list of scientific research reports with L933-0457 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L933-0457?
Check Price and Availability of L933-0457, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L933-0457 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L933-0457
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L933-0457
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L933-0457 available by request