L933-0469 Screening compound: 1-(5-chloro-2,4-dimethoxyphenyl)-3-{1-[3-oxo-4-(prop-2-en-1-yl)-3H,4H-pyrido[2,3-b]pyrazin-2-yl]piperidin-4-yl}urea

L933-0469 Screening compound: 1-(5-chloro-2,4-dimethoxyphenyl)-3-{1-[3-oxo-4-(prop-2-en-1-yl)-3H,4H-pyrido[2,3-b]pyrazin-2-yl]piperidin-4-yl}urea
L933-0469 Screening compound: 1-(5-chloro-2,4-dimethoxyphenyl)-3-{1-[3-oxo-4-(prop-2-en-1-yl)-3H,4H-pyrido[2,3-b]pyrazin-2-yl]piperidin-4-yl}urea alternative view

Chemical Structure Depiction of ChemDiv screening compound L933-0469
1-(5-chloro-2,4-dimethoxyphenyl)-3-{1-[3-oxo-4-(prop-2-en-1-yl)-3H,4H-pyrido[2,3-b]pyrazin-2-yl]piperidin-4-yl}urea

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L933-0469

Molecular Formula

C24H27ClN6O4 (C24 H27 ClN6 O4)

Compound Name

1-(5-chloro-2,4-dimethoxyphenyl)-3-{1-[3-oxo-4-(prop-2-en-1-yl)-3H,4H-pyrido[2,3-b]pyrazin-2-yl]piperidin-4-yl}urea

IUPAC name

1-(5-chloro-24-dimethoxyphenyl)-3-{1-[3-oxo-4-(prop-2-en-1-yl)-3H4H-pyrido[23-b]pyrazin-2-yl]piperidin-4-yl}urea

SMILES

COc(c(NC(NC(CC1)CCN1C(C(N1CC=C)=O)=Nc2c1nccc2)=O)c1)cc(OC)c1Cl

InChI

InChI=1S/C24H27ClN6O4/c1-4-10-31-21-17(6-5-9-26-21)28-22(23(31)32)30-11-7-15(8-12-30)27-24(33)29-18-13-16(25)19(34-2)14-20(18)35-3/h4-6,9,13-15H,1,7-8,10-12H2,2-3H3,(H2,27,29,33)

InChI Key

QDXCFPDTXFQDGO-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27488262

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

498.97

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

9.00

Number of Nitrogen and Oxygen Atoms

10

Partition Coefficient, logP

2.674

Distribution Coefficient, logD

2.674

Water Solubility, LogSw

-3.49

Polar Surface Area

84.522

Acid Dissociation Constant (pKa)

10.61

Base Dissociation Constant (pKb)

4.12

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

33.30

L933-0469 in Drug Discovery

Included in Screening Libraries

Chelators targeting matrix metalloproteinases library (8930 compounds)

Anti-HIV1 Library (19540 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Cardiovascular
  • Antiviral
  • Infections
  • Immune system
Targets:
  • Proteases

References: we are preparing a list of scientific research reports with L933-0469 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L933-0469?
Check Price and Availability of L933-0469, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L933-0469 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L933-0469
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L933-0469
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L933-0469 available by request