L933-0476 Screening compound: 3-(3-ethoxypropyl)-1-{1-[3-oxo-4-(prop-2-en-1-yl)-3H,4H-pyrido[2,3-b]pyrazin-2-yl]piperidin-4-yl}urea

L933-0476 Screening compound: 3-(3-ethoxypropyl)-1-{1-[3-oxo-4-(prop-2-en-1-yl)-3H,4H-pyrido[2,3-b]pyrazin-2-yl]piperidin-4-yl}urea
L933-0476 Screening compound: 3-(3-ethoxypropyl)-1-{1-[3-oxo-4-(prop-2-en-1-yl)-3H,4H-pyrido[2,3-b]pyrazin-2-yl]piperidin-4-yl}urea alternative view

Chemical Structure Depiction of ChemDiv screening compound L933-0476
3-(3-ethoxypropyl)-1-{1-[3-oxo-4-(prop-2-en-1-yl)-3H,4H-pyrido[2,3-b]pyrazin-2-yl]piperidin-4-yl}urea

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L933-0476

Molecular Formula

C21H30N6O3 (C21 H30 N6 O3)

Compound Name

3-(3-ethoxypropyl)-1-{1-[3-oxo-4-(prop-2-en-1-yl)-3H,4H-pyrido[2,3-b]pyrazin-2-yl]piperidin-4-yl}urea

IUPAC name

3-(3-ethoxypropyl)-1-{1-[3-oxo-4-(prop-2-en-1-yl)-3H4H-pyrido[23-b]pyrazin-2-yl]piperidin-4-yl}urea

SMILES

CCOCCCNC(NC(CC1)CCN1C1=Nc2cccnc2N(CC=C)C1=O)=O

InChI

InChI=1S/C21H30N6O3/c1-3-12-27-18-17(7-5-10-22-18)25-19(20(27)28)26-13-8-16(9-14-26)24-21(29)23-11-6-15-30-4-2/h3,5,7,10,16H,1,4,6,8-9,11-15H2,2H3,(H2,23,24,29)

InChI Key

MISBYEPZULPZMW-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27488267

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

414.51

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

11.00

Number of Nitrogen and Oxygen Atoms

9

Partition Coefficient, logP

1.058

Distribution Coefficient, logD

1.057

Water Solubility, LogSw

-1.91

Polar Surface Area

79.372

Acid Dissociation Constant (pKa)

17.26

Base Dissociation Constant (pKb)

4.12

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

52.40

L933-0476 in Drug Discovery

Included in Screening Libraries

Chelators targeting matrix metalloproteinases library (8930 compounds)

Eccentric PPI Library (11937 compounds)

Protein-Protein Interaction Library (218420 compounds)

Targeted Diversity Library (40567 compounds)

Anti-HIV1 Library (19540 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Cardiovascular
  • Antiviral
  • Infections
  • Immune system
Targets:
  • Proteases
Mechanism of action:
  • PPI modulators
  • PPI modulators
Structure:
  • Cyclic compounds

References: we are preparing a list of scientific research reports with L933-0476 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L933-0476?
Check Price and Availability of L933-0476, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L933-0476 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L933-0476
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L933-0476
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L933-0476 available by request