L934-0063 Screening compound: N-{5-[1-(4-methoxyphenyl)-5-oxopyrrolidin-3-yl]-1,3,4-oxadiazol-2-yl}-4-(trifluoromethyl)benzamide

L934-0063 Screening compound: N-{5-[1-(4-methoxyphenyl)-5-oxopyrrolidin-3-yl]-1,3,4-oxadiazol-2-yl}-4-(trifluoromethyl)benzamide
L934-0063 Screening compound: N-{5-[1-(4-methoxyphenyl)-5-oxopyrrolidin-3-yl]-1,3,4-oxadiazol-2-yl}-4-(trifluoromethyl)benzamide alternative view

Chemical Structure Depiction of ChemDiv screening compound L934-0063
N-{5-[1-(4-methoxyphenyl)-5-oxopyrrolidin-3-yl]-1,3,4-oxadiazol-2-yl}-4-(trifluoromethyl)benzamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L934-0063

Molecular Formula

C21H17F3N4O4 (C21 H17 F3 N4 O4)

Compound Name

N-{5-[1-(4-methoxyphenyl)-5-oxopyrrolidin-3-yl]-1,3,4-oxadiazol-2-yl}-4-(trifluoromethyl)benzamide

IUPAC name

N-{5-[1-(4-methoxyphenyl)-5-oxopyrrolidin-3-yl]-134-oxadiazol-2-yl}-4-(trifluoromethyl)benzamide

SMILES

COc(cc1)ccc1N(CC(C1)c2nnc(NC(c3ccc(C(F)(F)F)cc3)=O)o2)C1=O

InChI

InChI=1S/C21H17F3N4O4/c1-31-16-8-6-15(7-9-16)28-11-13(10-17(28)29)19-26-27-20(32-19)25-18(30)12-2-4-14(5-3-12)21(22,23)24/h2-9,13H,10-11H2,1H3,(H,25,27,30)/t13-/m0/s1

InChI Key

ZQEIKYOOOUIXRP-ZDUSSCGKSA-N

MDL Number (MFCD)

MFCD15137546

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

446.39

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

2.858

Distribution Coefficient, logD

1.105

Water Solubility, LogSw

-3.33

Polar Surface Area

79.452

Acid Dissociation Constant (pKa)

5.66

Base Dissociation Constant (pKb)

-1.37

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

23.80

L934-0063 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

C-Met Library (15277 compounds)

Protein-Protein Interaction Library (218420 compounds)

Beyond the Flatland Library sp3 enriched (92988 compounds)

Type II Kinase Inhibitors Library (6956 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Endocrine
  • Digestive system
  • Hemic and lymphatic
  • Endocrine
Targets:
  • Kinases
  • Kinases
Mechanism of action:
  • Receptor's ligands
  • PPI modulators
Structure:
  • Cyclic compounds

References: we are preparing a list of scientific research reports with L934-0063 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L934-0063?
Check Price and Availability of L934-0063, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L934-0063 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L934-0063
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L934-0063
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L934-0063 available by request