L934-0643 Screening compound: N-{5-[1-(4-methanesulfonylphenyl)-5-oxopyrrolidin-3-yl]-1,3,4-oxadiazol-2-yl}thiophene-2-carboxamide

L934-0643 Screening compound: N-{5-[1-(4-methanesulfonylphenyl)-5-oxopyrrolidin-3-yl]-1,3,4-oxadiazol-2-yl}thiophene-2-carboxamide
L934-0643 Screening compound: N-{5-[1-(4-methanesulfonylphenyl)-5-oxopyrrolidin-3-yl]-1,3,4-oxadiazol-2-yl}thiophene-2-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound L934-0643
N-{5-[1-(4-methanesulfonylphenyl)-5-oxopyrrolidin-3-yl]-1,3,4-oxadiazol-2-yl}thiophene-2-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L934-0643

Molecular Formula

C18H16N4O5S2 (C18 H16 N4 O5 S2)

Compound Name

N-{5-[1-(4-methanesulfonylphenyl)-5-oxopyrrolidin-3-yl]-1,3,4-oxadiazol-2-yl}thiophene-2-carboxamide

IUPAC name

n/a

SMILES

CS(c(cc1)ccc1N(CC(C1)c2nnc(NC(c3cccs3)=O)o2)C1=O)(=O)=O

InChI

InChI=1S/C18H16N4O5S2/c1-29(25,26)13-6-4-12(5-7-13)22-10-11(9-15(22)23)17-20-21-18(27-17)19-16(24)14-3-2-8-28-14/h2-8,11H,9-10H2,1H3,(H,19,21,24)/t11-/m1/s1

InChI Key

TXWYWALGWJCDMS-LLVKDONJSA-N

MDL Number (MFCD)

MFCD27488462

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

432.48

Hydrogen Bond Acceptors Count

11.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

9

Partition Coefficient, logP

0.732

Distribution Coefficient, logD

-0.086

Water Solubility, LogSw

-2.38

Polar Surface Area

102.675

Acid Dissociation Constant (pKa)

6.65

Base Dissociation Constant (pKb)

-2.60

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

22.20

L934-0643 in Drug Discovery

Included in Screening Libraries

C-Met Library (15277 compounds)

Protein-Protein Interaction Library (218420 compounds)

Beyond the Flatland Library sp3 enriched (92988 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Endocrine
Targets:
  • Kinases
Mechanism of action:
  • Receptor's ligands
  • PPI modulators
Structure:
  • Cyclic compounds

References: we are preparing a list of scientific research reports with L934-0643 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L934-0643?
Check Price and Availability of L934-0643, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L934-0643 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L934-0643
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L934-0643
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L934-0643 available by request