L940-0130 Screening compound: 3-{2-[(2-chloro-6-fluorophenyl)methyl]-1,5-dioxo-1H,2H,4H,5H-[1,2,4]triazolo[4,3-a]quinazolin-4-yl}-N-cyclopentylpropanamide

L940-0130 Screening compound: 3-{2-[(2-chloro-6-fluorophenyl)methyl]-1,5-dioxo-1H,2H,4H,5H-[1,2,4]triazolo[4,3-a]quinazolin-4-yl}-N-cyclopentylpropanamide
L940-0130 Screening compound: 3-{2-[(2-chloro-6-fluorophenyl)methyl]-1,5-dioxo-1H,2H,4H,5H-[1,2,4]triazolo[4,3-a]quinazolin-4-yl}-N-cyclopentylpropanamide alternative view

Chemical Structure Depiction of ChemDiv screening compound L940-0130
3-{2-[(2-chloro-6-fluorophenyl)methyl]-1,5-dioxo-1H,2H,4H,5H-[1,2,4]triazolo[4,3-a]quinazolin-4-yl}-N-cyclopentylpropanamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L940-0130

Molecular Formula

C24H23ClFN5O3 (C24 H23 ClFN5 O3)

Compound Name

3-{2-[(2-chloro-6-fluorophenyl)methyl]-1,5-dioxo-1H,2H,4H,5H-[1,2,4]triazolo[4,3-a]quinazolin-4-yl}-N-cyclopentylpropanamide

IUPAC name

3-{2-[(2-chloro-6-fluorophenyl)methyl]-15-dioxo-1H2H4H5H-[124]triazolo[43-a]quinazolin-4-yl}-N-cyclopentylpropanamide

SMILES

O=C(CCN(C(N1c2c3cccc2)=NN(Cc(c(F)ccc2)c2Cl)C1=O)C3=O)NC1CCCC1

InChI

InChI=1S/C24H23ClFN5O3/c25-18-9-5-10-19(26)17(18)14-30-24(34)31-20-11-4-3-8-16(20)22(33)29(23(31)28-30)13-12-21(32)27-15-6-1-2-7-15/h3-5,8-11,15H,1-2,6-7,12-14H2,(H,27,32)

InChI Key

UKIIXUGWEJZLKC-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27488719

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

483.93

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

3.665

Distribution Coefficient, logD

3.665

Water Solubility, LogSw

-4.26

Polar Surface Area

72.476

Acid Dissociation Constant (pKa)

15.80

Base Dissociation Constant (pKb)

0.64

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

33.30

L940-0130 in Drug Discovery

Included in Screening Libraries

Serine Proteases Inhibitors Library (32732 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Infections
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Cardiovascular
  • Skin
  • Metabolic
  • Immune system
Targets:
  • Proteases

References: we are preparing a list of scientific research reports with L940-0130 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L940-0130?
Check Price and Availability of L940-0130, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L940-0130 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L940-0130
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L940-0130
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L940-0130 available by request