L946-0377 Screening compound: N-(4-fluorophenyl)-4-{5-[1-(4-methylbenzoyl)piperidin-4-yl]-1,2,4-oxadiazol-3-yl}benzamide

L946-0377 Screening compound: N-(4-fluorophenyl)-4-{5-[1-(4-methylbenzoyl)piperidin-4-yl]-1,2,4-oxadiazol-3-yl}benzamide
L946-0377 Screening compound: N-(4-fluorophenyl)-4-{5-[1-(4-methylbenzoyl)piperidin-4-yl]-1,2,4-oxadiazol-3-yl}benzamide alternative view

Chemical Structure Depiction of ChemDiv screening compound L946-0377
N-(4-fluorophenyl)-4-{5-[1-(4-methylbenzoyl)piperidin-4-yl]-1,2,4-oxadiazol-3-yl}benzamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L946-0377

Molecular Formula

C28H25FN4O3 (C28 H25 FN4 O3)

Compound Name

N-(4-fluorophenyl)-4-{5-[1-(4-methylbenzoyl)piperidin-4-yl]-1,2,4-oxadiazol-3-yl}benzamide

IUPAC name

N-(4-fluorophenyl)-4-{5-[1-(4-methylbenzoyl)piperidin-4-yl]-124-oxadiazol-3-yl}benzamide

SMILES

Cc(cc1)ccc1C(N(CC1)CCC1c1nc(-c(cc2)ccc2C(Nc(cc2)ccc2F)=O)no1)=O

InChI

InChI=1S/C28H25FN4O3/c1-18-2-4-22(5-3-18)28(35)33-16-14-21(15-17-33)27-31-25(32-36-27)19-6-8-20(9-7-19)26(34)30-24-12-10-23(29)11-13-24/h2-13,21H,14-17H2,1H3,(H,30,34)

InChI Key

OYCKBVTUCJKGKF-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27488938

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

484.53

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

5.406

Distribution Coefficient, logD

5.403

Water Solubility, LogSw

-5.41

Polar Surface Area

71.384

Acid Dissociation Constant (pKa)

9.49

Base Dissociation Constant (pKb)

-3.03

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

21.40

L946-0377 in Drug Discovery

Included in Screening Libraries

3D-Diversity Natural-Product-Like Library (18102 compounds)

Included in 1.7M Stock Database

Structure:
  • 3D

References: we are preparing a list of scientific research reports with L946-0377 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L946-0377?
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What is the minimum amount of L946-0377 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L946-0377
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L946-0377
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L946-0377 available by request