L948-0688 Screening compound: 1-(4-methylbenzenesulfonyl)-3-{2-[3-(2-methylphenyl)-1,2,4-oxadiazol-5-yl]pyrrolidine-1-carbonyl}piperidine

L948-0688 Screening compound: 1-(4-methylbenzenesulfonyl)-3-{2-[3-(2-methylphenyl)-1,2,4-oxadiazol-5-yl]pyrrolidine-1-carbonyl}piperidine
L948-0688 Screening compound: 1-(4-methylbenzenesulfonyl)-3-{2-[3-(2-methylphenyl)-1,2,4-oxadiazol-5-yl]pyrrolidine-1-carbonyl}piperidine alternative view

Chemical Structure Depiction of ChemDiv screening compound L948-0688
1-(4-methylbenzenesulfonyl)-3-{2-[3-(2-methylphenyl)-1,2,4-oxadiazol-5-yl]pyrrolidine-1-carbonyl}piperidine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L948-0688

Molecular Formula

C26H30N4O4S (C26 H30 N4 O4 S)

Compound Name

1-(4-methylbenzenesulfonyl)-3-{2-[3-(2-methylphenyl)-1,2,4-oxadiazol-5-yl]pyrrolidine-1-carbonyl}piperidine

IUPAC name

1-(4-methylbenzenesulfonyl)-3-{2-[3-(2-methylphenyl)-124-oxadiazol-5-yl]pyrrolidine-1-carbonyl}piperidine

SMILES

Cc(cc1)ccc1S(N(CCC1)CC1C(N(CCC1)C1c1nc(-c2c(C)cccc2)no1)=O)(=O)=O

InChI

InChI=1S/C26H30N4O4S/c1-18-11-13-21(14-12-18)35(32,33)29-15-5-8-20(17-29)26(31)30-16-6-10-23(30)25-27-24(28-34-25)22-9-4-3-7-19(22)2/h3-4,7,9,11-14,20,23H,5-6,8,10,15-17H2,1-2H3

InChI Key

LZWCZDIZSVTPNM-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27489007

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

494.61

Hydrogen Bond Acceptors Count

10.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

4.338

Distribution Coefficient, logD

4.338

Water Solubility, LogSw

-4.34

Polar Surface Area

79.997

Acid Dissociation Constant (pKa)

22.98

Base Dissociation Constant (pKb)

-4.15

Number of Chiral Centers

2.00

Percent sp3 carbon bonding

42.30

L948-0688 in Drug Discovery

Included in Screening Libraries

Nonpeptide Peptidomimetics PPI Library (18997 compounds)

Protein Arginine Methyltransferases Library (27925 compounds)

Protein-Protein Interaction Library (218420 compounds)

SmartTM Library (51161 compounds)

Included in 1.7M Stock Database

Mechanism of action:
  • PPI modulators
  • Epigenetic
  • PPI modulators
Structure:
  • Mimetics
Therapeutical areas:
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Metabolic
Targets:
  • Others

References: we are preparing a list of scientific research reports with L948-0688 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L948-0688?
Check Price and Availability of L948-0688, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L948-0688 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L948-0688
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L948-0688
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L948-0688 available by request