L948-1428 Screening compound: 1-{2-[3-(3-methylphenyl)-1,2,4-oxadiazol-5-yl]pyrrolidin-1-yl}-2-phenylpropan-1-one

L948-1428 Screening compound: 1-{2-[3-(3-methylphenyl)-1,2,4-oxadiazol-5-yl]pyrrolidin-1-yl}-2-phenylpropan-1-one
L948-1428 Screening compound: 1-{2-[3-(3-methylphenyl)-1,2,4-oxadiazol-5-yl]pyrrolidin-1-yl}-2-phenylpropan-1-one alternative view

Chemical Structure Depiction of ChemDiv screening compound L948-1428
1-{2-[3-(3-methylphenyl)-1,2,4-oxadiazol-5-yl]pyrrolidin-1-yl}-2-phenylpropan-1-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L948-1428

Molecular Formula

C22H23N3O2 (C22 H23 N3 O2)

Compound Name

1-{2-[3-(3-methylphenyl)-1,2,4-oxadiazol-5-yl]pyrrolidin-1-yl}-2-phenylpropan-1-one

IUPAC name

1-{2-[3-(3-methylphenyl)-124-oxadiazol-5-yl]pyrrolidin-1-yl}-2-phenylpropan-1-one

SMILES

CC(C(N(CCC1)C1c1nc(-c2cc(C)ccc2)no1)=O)c1ccccc1

InChI

InChI=1S/C22H23N3O2/c1-15-8-6-11-18(14-15)20-23-21(27-24-20)19-12-7-13-25(19)22(26)16(2)17-9-4-3-5-10-17/h3-6,8-11,14,16,19H,7,12-13H2,1-2H3

InChI Key

FRDKSUVOHJHPIG-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27489035

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

361.44

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

5.092

Distribution Coefficient, logD

5.092

Water Solubility, LogSw

-4.89

Polar Surface Area

48.352

Acid Dissociation Constant (pKa)

18.38

Base Dissociation Constant (pKb)

-5.19

Number of Chiral Centers

2.00

Percent sp3 carbon bonding

31.80

L948-1428 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Serine Proteases Inhibitors Library (32732 compounds)

SmartTM Library (51161 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Infections
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Cardiovascular
  • Skin
  • Metabolic
  • Immune system
Targets:
  • Proteases

References: we are preparing a list of scientific research reports with L948-1428 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L948-1428?
Check Price and Availability of L948-1428, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L948-1428 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L948-1428
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L948-1428
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L948-1428 available by request