L948-1834 Screening compound: 3-{2-[3-(3-chlorophenyl)-1,2,4-oxadiazol-5-yl]pyrrolidine-1-carbonyl}-2-(methylsulfanyl)pyridine

L948-1834 Screening compound: 3-{2-[3-(3-chlorophenyl)-1,2,4-oxadiazol-5-yl]pyrrolidine-1-carbonyl}-2-(methylsulfanyl)pyridine
L948-1834 Screening compound: 3-{2-[3-(3-chlorophenyl)-1,2,4-oxadiazol-5-yl]pyrrolidine-1-carbonyl}-2-(methylsulfanyl)pyridine alternative view

Chemical Structure Depiction of ChemDiv screening compound L948-1834
3-{2-[3-(3-chlorophenyl)-1,2,4-oxadiazol-5-yl]pyrrolidine-1-carbonyl}-2-(methylsulfanyl)pyridine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L948-1834

Molecular Formula

C19H17ClN4O2S (C19 H17 ClN4 O2 S)

Compound Name

3-{2-[3-(3-chlorophenyl)-1,2,4-oxadiazol-5-yl]pyrrolidine-1-carbonyl}-2-(methylsulfanyl)pyridine

IUPAC name

3-{2-[3-(3-chlorophenyl)-124-oxadiazol-5-yl]pyrrolidine-1-carbonyl}-2-(methylsulfanyl)pyridine

SMILES

CSc(nccc1)c1C(N(CCC1)C1c1nc(-c2cccc(Cl)c2)no1)=O

InChI

InChI=1S/C19H17ClN4O2S/c1-27-18-14(7-3-9-21-18)19(25)24-10-4-8-15(24)17-22-16(23-26-17)12-5-2-6-13(20)11-12/h2-3,5-7,9,11,15H,4,8,10H2,1H3/t15-/m0/s1

InChI Key

GUHSDVPABSNHJQ-HNNXBMFYSA-N

MDL Number (MFCD)

MFCD27489069

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

400.89

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

4.322

Distribution Coefficient, logD

4.322

Water Solubility, LogSw

-4.58

Polar Surface Area

57.532

Acid Dissociation Constant (pKa)

25.29

Base Dissociation Constant (pKb)

2.05

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

26.30

L948-1834 in Drug Discovery

Included in Screening Libraries

3D-Pharmacophore Based Diversity Library (49813 compounds)

KRAS-Targeted Library (16000 compounds)

Protein-Protein Interaction Library (218420 compounds)

Serine Proteases Inhibitors Library (32732 compounds)

SmartTM Library (51161 compounds)

Beyond the Flatland Library sp3 enriched (92988 compounds)

MDM2-p53 interaction inhibitors Library (21687 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Infections
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Cardiovascular
  • Skin
  • Metabolic
  • Immune system
  • Cancer
Targets:
  • Kinases
  • Proteases
Mechanism of action:
  • PPI modulators
  • PPI modulators
Structure:
  • Cyclic compounds

References: we are preparing a list of scientific research reports with L948-1834 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L948-1834?
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What is the minimum amount of L948-1834 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L948-1834
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L948-1834
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L948-1834 available by request