L949-0081 Screening compound: N-(3-fluorophenyl)-2-(3-phenyl-1,2,4-oxadiazol-5-yl)pyrrolidine-1-carboxamide

L949-0081 Screening compound: N-(3-fluorophenyl)-2-(3-phenyl-1,2,4-oxadiazol-5-yl)pyrrolidine-1-carboxamide
L949-0081 Screening compound: N-(3-fluorophenyl)-2-(3-phenyl-1,2,4-oxadiazol-5-yl)pyrrolidine-1-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound L949-0081
N-(3-fluorophenyl)-2-(3-phenyl-1,2,4-oxadiazol-5-yl)pyrrolidine-1-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L949-0081

Molecular Formula

C19H17FN4O2 (C19 H17 FN4 O2)

Compound Name

N-(3-fluorophenyl)-2-(3-phenyl-1,2,4-oxadiazol-5-yl)pyrrolidine-1-carboxamide

IUPAC name

N-(3-fluorophenyl)-2-(3-phenyl-124-oxadiazol-5-yl)pyrrolidine-1-carboxamide

SMILES

O=C(Nc1cccc(F)c1)N(CCC1)C1c1nc(-c2ccccc2)no1

InChI

InChI=1S/C19H17FN4O2/c20-14-8-4-9-15(12-14)21-19(25)24-11-5-10-16(24)18-22-17(23-26-18)13-6-2-1-3-7-13/h1-4,6-9,12,16H,5,10-11H2,(H,21,25)/t16-/m0/s1

InChI Key

FSZZBVOCSBNUCT-INIZCTEOSA-N

MDL Number (MFCD)

MFCD14366861

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

352.37

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

4.213

Distribution Coefficient, logD

4.213

Water Solubility, LogSw

-4.21

Polar Surface Area

57.173

Acid Dissociation Constant (pKa)

12.65

Base Dissociation Constant (pKb)

-0.42

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

21.10

L949-0081 in Drug Discovery

Included in Screening Libraries

Protein-Protein Interaction Library (218420 compounds)

Serine Proteases Inhibitors Library (32732 compounds)

SmartTM Library (51161 compounds)

Beyond the Flatland Library sp3 enriched (92988 compounds)

Included in 1.7M Stock Database

Mechanism of action:
  • PPI modulators
Therapeutical areas:
  • Infections
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Cardiovascular
  • Skin
  • Metabolic
  • Immune system
Targets:
  • Proteases
Structure:
  • Cyclic compounds

References: we are preparing a list of scientific research reports with L949-0081 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L949-0081?
Check Price and Availability of L949-0081, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L949-0081 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L949-0081
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L949-0081
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L949-0081 available by request