L949-2918 Screening compound: N-(3,5-dimethoxyphenyl)-2-[3-(4-methoxyphenyl)-1,2,4-oxadiazol-5-yl]pyrrolidine-1-carboxamide

L949-2918 Screening compound: N-(3,5-dimethoxyphenyl)-2-[3-(4-methoxyphenyl)-1,2,4-oxadiazol-5-yl]pyrrolidine-1-carboxamide
L949-2918 Screening compound: N-(3,5-dimethoxyphenyl)-2-[3-(4-methoxyphenyl)-1,2,4-oxadiazol-5-yl]pyrrolidine-1-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound L949-2918
N-(3,5-dimethoxyphenyl)-2-[3-(4-methoxyphenyl)-1,2,4-oxadiazol-5-yl]pyrrolidine-1-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L949-2918

Molecular Formula

C22H24N4O5 (C22 H24 N4 O5)

Compound Name

N-(3,5-dimethoxyphenyl)-2-[3-(4-methoxyphenyl)-1,2,4-oxadiazol-5-yl]pyrrolidine-1-carboxamide

IUPAC name

N-(35-dimethoxyphenyl)-2-[3-(4-methoxyphenyl)-124-oxadiazol-5-yl]pyrrolidine-1-carboxamide

SMILES

COc(cc1)ccc1-c1noc(C(CCC2)N2C(Nc2cc(OC)cc(OC)c2)=O)n1

InChI

InChI=1S/C22H24N4O5/c1-28-16-8-6-14(7-9-16)20-24-21(31-25-20)19-5-4-10-26(19)22(27)23-15-11-17(29-2)13-18(12-15)30-3/h6-9,11-13,19H,4-5,10H2,1-3H3,(H,23,27)/t19-/m0/s1

InChI Key

AIQPTHXXWRJWQZ-IBGZPJMESA-N

MDL Number (MFCD)

MFCD14366777

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

424.46

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

9

Partition Coefficient, logP

4.287

Distribution Coefficient, logD

4.287

Water Solubility, LogSw

-4.23

Polar Surface Area

79.805

Acid Dissociation Constant (pKa)

12.57

Base Dissociation Constant (pKb)

0.48

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

31.80

L949-2918 in Drug Discovery

Included in Screening Libraries

3D-Pharmacophore Based Diversity Library (49813 compounds)

Protein-Protein Interaction Library (218420 compounds)

SmartTM Library (51161 compounds)

Beyond the Flatland Library sp3 enriched (92988 compounds)

PD-1/L1 Library (498 compounds)

Included in 1.7M Stock Database

Mechanism of action:
  • PPI modulators
Structure:
  • Cyclic compounds
Therapeutical areas:
  • Cancer
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Immune system
Targets:
  • Others

References: we are preparing a list of scientific research reports with L949-2918 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L949-2918?
Check Price and Availability of L949-2918, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L949-2918 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L949-2918
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L949-2918
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L949-2918 available by request