L949-3165 Screening compound: 2-[3-(2,4-difluorophenyl)-1,2,4-oxadiazol-5-yl]-N-(4-methoxyphenyl)pyrrolidine-1-carboxamide

L949-3165 Screening compound: 2-[3-(2,4-difluorophenyl)-1,2,4-oxadiazol-5-yl]-N-(4-methoxyphenyl)pyrrolidine-1-carboxamide
L949-3165 Screening compound: 2-[3-(2,4-difluorophenyl)-1,2,4-oxadiazol-5-yl]-N-(4-methoxyphenyl)pyrrolidine-1-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound L949-3165
2-[3-(2,4-difluorophenyl)-1,2,4-oxadiazol-5-yl]-N-(4-methoxyphenyl)pyrrolidine-1-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L949-3165

Molecular Formula

C20H18F2N4O3 (C20 H18 F2 N4 O3)

Compound Name

2-[3-(2,4-difluorophenyl)-1,2,4-oxadiazol-5-yl]-N-(4-methoxyphenyl)pyrrolidine-1-carboxamide

IUPAC name

2-[3-(24-difluorophenyl)-124-oxadiazol-5-yl]-N-(4-methoxyphenyl)pyrrolidine-1-carboxamide

SMILES

COc(cc1)ccc1NC(N(CCC1)C1c1nc(-c(ccc(F)c2)c2F)no1)=O

InChI

InChI=1S/C20H18F2N4O3/c1-28-14-7-5-13(6-8-14)23-20(27)26-10-2-3-17(26)19-24-18(25-29-19)15-9-4-12(21)11-16(15)22/h4-9,11,17H,2-3,10H2,1H3,(H,23,27)/t17-/m0/s1

InChI Key

BXKQWXYHSLMLQN-KRWDZBQOSA-N

MDL Number (MFCD)

MFCD27489423

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

400.38

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

4.175

Distribution Coefficient, logD

4.175

Water Solubility, LogSw

-4.27

Polar Surface Area

64.717

Acid Dissociation Constant (pKa)

14.20

Base Dissociation Constant (pKb)

0.56

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

25.00

L949-3165 in Drug Discovery

Included in Screening Libraries

Antifungal Library (16415 compounds)

Protein-Protein Interaction Library (218420 compounds)

SmartTM Library (51161 compounds)

Beyond the Flatland Library sp3 enriched (92988 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Infections
  • Immune system
  • animal
Agro:
  • Agro
Mechanism of action:
  • PPI modulators
Structure:
  • Cyclic compounds

References: we are preparing a list of scientific research reports with L949-3165 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L949-3165?
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What is the minimum amount of L949-3165 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L949-3165
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L949-3165
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L949-3165 available by request