L949-3193 Screening compound: 2-[3-(2,4-difluorophenyl)-1,2,4-oxadiazol-5-yl]-N-(2,4-dimethoxyphenyl)pyrrolidine-1-carboxamide

L949-3193 Screening compound: 2-[3-(2,4-difluorophenyl)-1,2,4-oxadiazol-5-yl]-N-(2,4-dimethoxyphenyl)pyrrolidine-1-carboxamide
L949-3193 Screening compound: 2-[3-(2,4-difluorophenyl)-1,2,4-oxadiazol-5-yl]-N-(2,4-dimethoxyphenyl)pyrrolidine-1-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound L949-3193
2-[3-(2,4-difluorophenyl)-1,2,4-oxadiazol-5-yl]-N-(2,4-dimethoxyphenyl)pyrrolidine-1-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L949-3193

Molecular Formula

C21H20F2N4O4 (C21 H20 F2 N4 O4)

Compound Name

2-[3-(2,4-difluorophenyl)-1,2,4-oxadiazol-5-yl]-N-(2,4-dimethoxyphenyl)pyrrolidine-1-carboxamide

IUPAC name

2-[3-(24-difluorophenyl)-124-oxadiazol-5-yl]-N-(24-dimethoxyphenyl)pyrrolidine-1-carboxamide

SMILES

COc(cc1)cc(OC)c1NC(N(CCC1)C1c1nc(-c(ccc(F)c2)c2F)no1)=O

InChI

InChI=1S/C21H20F2N4O4/c1-29-13-6-8-16(18(11-13)30-2)24-21(28)27-9-3-4-17(27)20-25-19(26-31-20)14-7-5-12(22)10-15(14)23/h5-8,10-11,17H,3-4,9H2,1-2H3,(H,24,28)/t17-/m0/s1

InChI Key

NJXAXXBEEGKRHW-KRWDZBQOSA-N

MDL Number (MFCD)

MFCD27489436

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

430.41

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

4.334

Distribution Coefficient, logD

4.334

Water Solubility, LogSw

-4.30

Polar Surface Area

71.650

Acid Dissociation Constant (pKa)

12.76

Base Dissociation Constant (pKb)

0.37

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

28.60

L949-3193 in Drug Discovery

Included in Screening Libraries

CNS Targets (44014 compounds)

Protein-Protein Interaction Library (218420 compounds)

SmartTM Library (51161 compounds)

Beyond the Flatland Library sp3 enriched (92988 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Nervous system
Mechanism of action:
  • PPI modulators
Structure:
  • Cyclic compounds

References: we are preparing a list of scientific research reports with L949-3193 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L949-3193?
Check Price and Availability of L949-3193, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L949-3193 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L949-3193
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L949-3193
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L949-3193 available by request