L957-0255 Screening compound: 5-[4-(pyrrolidine-1-sulfonyl)phenyl]-N-[3-(1,2,3,4-tetrahydroisoquinolin-2-yl)propyl]-1,3,4-oxadiazole-2-carboxamide

L957-0255 Screening compound: 5-[4-(pyrrolidine-1-sulfonyl)phenyl]-N-[3-(1,2,3,4-tetrahydroisoquinolin-2-yl)propyl]-1,3,4-oxadiazole-2-carboxamide
L957-0255 Screening compound: 5-[4-(pyrrolidine-1-sulfonyl)phenyl]-N-[3-(1,2,3,4-tetrahydroisoquinolin-2-yl)propyl]-1,3,4-oxadiazole-2-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound L957-0255
5-[4-(pyrrolidine-1-sulfonyl)phenyl]-N-[3-(1,2,3,4-tetrahydroisoquinolin-2-yl)propyl]-1,3,4-oxadiazole-2-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L957-0255

Molecular Formula

C25H29N5O4S (C25 H29 N5 O4 S)

Compound Name

5-[4-(pyrrolidine-1-sulfonyl)phenyl]-N-[3-(1,2,3,4-tetrahydroisoquinolin-2-yl)propyl]-1,3,4-oxadiazole-2-carboxamide

IUPAC name

5-[4-(pyrrolidine-1-sulfonyl)phenyl]-N-[3-(1234-tetrahydroisoquinolin-2-yl)propyl]-134-oxadiazole-2-carboxamide

SMILES

O=C(c1nnc(-c(cc2)ccc2S(N2CCCC2)(=O)=O)o1)NCCCN(CC1)Cc2c1cccc2

InChI

InChI=1S/C25H29N5O4S/c31-23(26-13-5-14-29-17-12-19-6-1-2-7-21(19)18-29)25-28-27-24(34-25)20-8-10-22(11-9-20)35(32,33)30-15-3-4-16-30/h1-2,6-11H,3-5,12-18H2,(H,26,31)

InChI Key

ZMJPOJSLIGCWTH-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27489610

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

495.6

Hydrogen Bond Acceptors Count

11.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

9.00

Number of Nitrogen and Oxygen Atoms

9

Partition Coefficient, logP

2.487

Distribution Coefficient, logD

1.337

Water Solubility, LogSw

-2.88

Polar Surface Area

90.730

Acid Dissociation Constant (pKa)

14.34

Base Dissociation Constant (pKb)

8.52

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

40.00

L957-0255 in Drug Discovery

Included in Screening Libraries

GPCR Targeted Library (31838 compounds)

Protein Kinases Inhibitors Library (36801 compounds)

Regenerative Medicine Focused Library (23016 compounds)

SmartTM Library (51161 compounds)

Peptidomimetic Library (37031 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Nervous system
  • Hemic and lymphatic
  • Cardiovascular
  • Musculoskeletal
  • Digestive system
  • Hemic and lymphatic
  • Cardiovascular
  • Skin
  • wounds
Targets:
  • GPCR
  • Kinases
Mechanism of action:
  • Receptor's ligands
  • PPI modulators
Structure:
  • Mimetics

References: we are preparing a list of scientific research reports with L957-0255 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L957-0255?
Check Price and Availability of L957-0255, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L957-0255 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L957-0255
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L957-0255
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L957-0255 available by request