L960-0345 Screening compound: N-benzyl-N-methyl-3-{[3-(4-methylphenyl)-6-oxo-1,6-dihydropyridazin-1-yl]methyl}-1,2,4-oxadiazole-5-carboxamide

L960-0345 Screening compound: N-benzyl-N-methyl-3-{[3-(4-methylphenyl)-6-oxo-1,6-dihydropyridazin-1-yl]methyl}-1,2,4-oxadiazole-5-carboxamide
L960-0345 Screening compound: N-benzyl-N-methyl-3-{[3-(4-methylphenyl)-6-oxo-1,6-dihydropyridazin-1-yl]methyl}-1,2,4-oxadiazole-5-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound L960-0345
N-benzyl-N-methyl-3-{[3-(4-methylphenyl)-6-oxo-1,6-dihydropyridazin-1-yl]methyl}-1,2,4-oxadiazole-5-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L960-0345

Molecular Formula

C23H21N5O3 (C23 H21 N5 O3)

Compound Name

N-benzyl-N-methyl-3-{[3-(4-methylphenyl)-6-oxo-1,6-dihydropyridazin-1-yl]methyl}-1,2,4-oxadiazole-5-carboxamide

IUPAC name

N-benzyl-N-methyl-3-{[3-(4-methylphenyl)-6-oxo-16-dihydropyridazin-1-yl]methyl}-124-oxadiazole-5-carboxamide

SMILES

Cc(cc1)ccc1C(C=C1)=NN(Cc2noc(C(N(C)Cc3ccccc3)=O)n2)C1=O

InChI

InChI=1S/C23H21N5O3/c1-16-8-10-18(11-9-16)19-12-13-21(29)28(25-19)15-20-24-22(31-26-20)23(30)27(2)14-17-6-4-3-5-7-17/h3-13H,14-15H2,1-2H3

InChI Key

ZAGWADMBLNFWNH-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27490101

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

415.45

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

3.267

Distribution Coefficient, logD

3.267

Water Solubility, LogSw

-3.19

Polar Surface Area

77.637

Acid Dissociation Constant (pKa)

27.84

Base Dissociation Constant (pKb)

1.03

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

17.40

L960-0345 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

C-Met Library (15277 compounds)

Protein Kinases Inhibitors Library (36801 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Endocrine
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Nervous system
  • Hemic and lymphatic
  • Cardiovascular
Targets:
  • Kinases
  • Kinases
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with L960-0345 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L960-0345?
Check Price and Availability of L960-0345, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L960-0345 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L960-0345
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L960-0345
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L960-0345 available by request